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基因诊断技术在脊柱结核诊断中的应用现状
引用本文:胡潮兴1,梁秋冬2. 基因诊断技术在脊柱结核诊断中的应用现状[J]. 新乡医学院学报, 2023, 0(1): 093-96. DOI: 10.7683/xxyxyxb.2023.01.017
作者姓名:胡潮兴1  梁秋冬2
作者单位:(1.新乡医学院第一附属医院,河南 卫辉 453100;2.新乡医学院第一附属医院脊柱与创伤外科二病区,河南 卫辉 453100)
摘    要:脊柱结核是一种常见的肺外结核病。近年来,随着脊柱结核患者逐年增多,不典型脊柱结核患者亦逐渐增多,而不典型脊柱结核诊断较为困难,需要与一般细菌感染、肿瘤以及非结核分枝杆菌感染相鉴别。基因诊断技术是一项诊断脊柱结核的重要工具,对临床不典型脊柱结核的诊断有较高价值。本文将对脊柱结核的流行现状、诊断及基因诊断技术进行综述,以帮助临床工作者对脊柱结核做出更加准确的诊断。

关 键 词:肺外结核  脊柱结核  结核分枝杆菌  基因诊断  分子生物学

Current situation of gene diagnosis technology in the diagnosis of spinal tuberculosis
HU Chaoxing1,LIANG Qiudong2. Current situation of gene diagnosis technology in the diagnosis of spinal tuberculosis[J]. Journal of Xinxiang Medical College, 2023, 0(1): 093-96. DOI: 10.7683/xxyxyxb.2023.01.017
Authors:HU Chaoxing1  LIANG Qiudong2
Affiliation:(1.The First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China;2.Department of Spinal and Trauma Surgery,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China)
Abstract:Spinal tuberculosis is a common extrapulmonary tuberculosis.In recent years,as the patients with spinal tuberculosis increases year by year,the patients with atypical spinal tuberculosis increases gradually.The diagnosis of atypical spinal tuberculosis is more difficult,which needs to be differentiated from general bacterial infection,tumor and non-Mycobacterium tuberculosis infection.Genetic diagnosis technology is an important tool for the diagnosis of spinal tuberculosis,which is of high value in the diagnosis of atypical spinal tuberculosis.This article will describe the epidemic situation,diagnosis and genetic diagnosis technology of spinal tuberculosis,so as to help clinical workers to make more accurate diagnosis of spinal tuberculosis.
Keywords:extrapulmonary tuberculosis  spinal tuberculosis  Mycobacterium tuberculosis  genetic diagnosis  molecular biology
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