三维能量多普勒超声在观察孕早期胎盘血流预测胎儿生长受限中的应用

目的 探讨三维能量多普勒超声对胎儿生长受限的预测价值研究。方法 选取2021年1—12月在医院建卡的正常孕妇400例作为研究对象，全部孕妇于孕早期11～13⁺⁶周应用三维能量多普勒超声检查胎盘，获得血管化-血流指数(VFI)、血管化指数(VI)、血流指数(FI)、胎盘体积(PV)、胎盘商(PQ)的水平。绘制受试者工作特征(ROC)曲线分析VFI、VI、FI、PV、PQ对胎儿生长受限的诊断效能。结果 正常孕妇400例出现胎儿生长受限35例，发生率为8.75%;将400例孕妇分为研究组35例(胎儿生长受限)和对照组365例(未发生胎儿生长受限)。两组的年龄、孕周、孕次、体质指数、初产妇的资料对比，差异无统计学意义(P>0.05)。研究组的PV、PQ均显著低于对照组，差异有统计学意义(P<0.05)。研究组的VFI、VI、FI均低于对照组，差异有统计学意义(P<0.05)。经ROC曲线分析，PV、VFI、VI的曲线下面积均高于0.7,且高于PQ、FI。PV、PQ、VFI、VI、FI的最大截断值分别为45.83、0.83、7.32、22.70、28.41...

Study on the predictive value of three-dimensional power Doppler ultrasound in fetal growth restriction

Objective To investigate the predictive value of three-dimensional power Doppler ultrasound in fetal growth restriction. Methods From January to December 2021, 400 normal pregnant women were selected. All pregnant women were examined by three-dimensional power Doppler ultrasound, and the levels of vascularization-flow index (VFI), vascularization index (VI), flow index (Fi), placental volume (PV) and placental quotient (PQ) were obtained. Receiver operating characteristic (ROC) curve was drawn to analyze the diagnostic efficacy of VFI, VI, Fi, PV and PQ for fetal growth restriction. Results There were 35 cases of fetal growth restriction in 400 normal pregnant women, the incidence rate was 8.75%; and they were divided into study group (35 cases with fetal growth restriction) and control group (365 cases without fetal growth restriction). There was no significant difference in age, gestational age, pregnancy times, body mass index or primipara data between the two groups (P>0.05). PV and PQ of the study group were significantly lower than those of the control group (P<0.05). The VFI, VI and Fi of the study group were significantly lower than those of the control group (P<0.05). By ROC curve analysis, the areas under the curve of PV, VFI and VI were higher than 0.7, and higher than PQ and Fi. As the cut-off values of PV, PQ, VFI, VI and Fi were 45.83, 0.83, 7.32, 22.70 and 28.41, respectively; the specificities were 77.89%, 67.74%, 58.32%, 57.99% and 74.80%, respectively; and the sensitivities were 53.72%, 73.10%, 96.88%, 97.60% and 58.42%, respectively. Conclusion Three dimensional power Doppler ultrasound has important predictive value for fetal growth restriction, and can provide quantifiable indicators for the diagnosis of fetal growth restriction.