| 1602例类风湿关节炎患者中医证候分布特点的多中心横断面调查 |
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| 引用本文： | 王建,巩勋,唐晓颇,刘宏潇,刘健,何东仪,张俊莉,李振彬,黄清春,王新昌,吴庆军,方勇飞,汪悦,陈适,蒋红,高明利,刘维,刘英,李泽光,赵钟文,王成武,刘维超,王海东,娄玉钤,孟庆良,阮崇杰,谢雁鸣,姜泉. 1602例类风湿关节炎患者中医证候分布特点的多中心横断面调查[J]. 中医杂志, 2018, 0(11): 963-967 |
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| 作者姓名： | 王建 巩勋 唐晓颇 刘宏潇 刘健 何东仪 张俊莉 李振彬 黄清春 王新昌 吴庆军 方勇飞 汪悦 陈适 蒋红 高明利 刘维 刘英 李泽光 赵钟文 王成武 刘维超 王海东 娄玉钤 孟庆良 阮崇杰 谢雁鸣 姜泉 |
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| 作者单位： | 中国中医科学院广安门医院;安徽中医药大学第一附属医院;上海市光华中西医结合医院;西安市第五医院;白求恩国际和平医院;广东省中医院;浙江中医药大学附属第二医院;北京协和医院;中国人民解放军第三军医大学附属医院;黑龙江中医药大学附属第一医院;福建省第二人民医院;长春中医药大学第一附属医院;云南省中医院;甘肃省中医院;河南风湿病医院;河南中医药大学第二附属医院;武汉市中医院;中国中医科学院中医临床基础医学研究所 |
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| 基金项目： | “十二五”国家科技支撑计划(2013BAI02B00) |
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| 摘 要： | 目的分析类风湿关节炎中医证候分布特点。方法采集全国18家研究中心1602例类风湿关节炎患者的病史及中西医诊断信息,设计类风湿关节炎病证规律调查表,将所有信息录入类风湿关节炎中医临床数据库。将患者辨证分为风湿痹阻证、寒湿痹阻证、湿热痹阻证、痰瘀痹阻证、气血两虚证、肝肾不足证。分析患者中医证候分布及组合特点。结果共收集符合标准的调查表1602份。因部分调查表证候诊断缺如,1418例证候填写完整的RA患者中,单一证候1232例占86.88%,其中湿热痹阻证比例最高共计622例,占43.86%,其他依次为寒湿痹阻证、肝肾不足证、痰瘀痹阻证、风湿痹阻证、气血不足证。RA患者不同证候分布差异具有统计学意义(P<0.05)。除西南地区外,其他各地区RA患者均以湿热痹阻证为主要证候,湿热痹阻证在华北地区的证候分布中所占比例最高为57.08%(137例/240例),西南地区最低为25.48%(66例/259例),西南地区以寒湿痹阻证为主要证候占32.82%(85例/259例)。各地区证候分布差异具有统计学意义(P<0.05)。痰瘀痹阻证、肝肾不足证病程与风湿痹阻证、寒湿痹阻证、湿热痹阻证、气血两虚证相比,差异具有统计学意义(P<0.05)。结论湿热痹阻证是类风湿关节炎患者的主要证候类型,其地域分布广,病程较痰瘀痹阻证、肝肾不足证患者短。
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| 关 键 词： | 类风湿关节炎 证候分布 湿热痹阻证 横断面调查 |
Multi-center Cross-sectional Survey of Characteristics of Chinese Medicine Syndromes in 1602 Rheumatoid Arthritis Patients |
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| WANG Jian,GONG Xun,TANG Xiaopo,LIU Hongxiao,LIU Jian,HE Dongyi,ZHANG Junli,LI Zhenbin,HUANG Qingchun,WANG Xinchang,WU Qingjun,FANG Yongfei,WANG Yue,CHEN Shi,JIANG Hong,GAO Mingli,LIU Wei,LIU Ying,LI Zeguang,ZHAO Zhongwen,WANG Chengwu,LIU Weichao,WANG Haidong,LOU Yuqian,MENG Qingliang,RUAN Chongjie,XlE Yanming,JIANG Quan. Multi-center Cross-sectional Survey of Characteristics of Chinese Medicine Syndromes in 1602 Rheumatoid Arthritis Patients[J]. Journal of Traditional Chinese Medicine, 2018, 0(11): 963-967 |
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| Authors: | WANG Jian GONG Xun TANG Xiaopo LIU Hongxiao LIU Jian HE Dongyi ZHANG Junli LI Zhenbin HUANG Qingchun WANG Xinchang WU Qingjun FANG Yongfei WANG Yue CHEN Shi JIANG Hong GAO Mingli LIU Wei LIU Ying LI Zeguang ZHAO Zhongwen WANG Chengwu LIU Weichao WANG Haidong LOU Yuqian MENG Qingliang RUAN Chongjie XlE Yanming JIANG Quan |
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| Affiliation: | (Guang＇anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053;The First Affiliated Hospital of Anhui University of Chinese Medicine;Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine;The Fifth Hospital of Xi＇an;Bethune International Peace Hospital;Guangdong Proyincial Hospital Of Traditional Chinese Medicine;The Second Affiliated Hospital of Zhejiang University of Chinese Medicine;Peking Union Medical College Hospital;Affiliated Hospital of the Third Military Medical University of the Chinese People＇s Liberation Army;6. First Affiliated Hospital, Heilongjiang University of Chinese Medicin;7. The Second People＇s Hospital of Fujian Provinc;8. The First Affiliated Hospital of Changehun University of Traditional Chinese Medicin;9. Yunnan Provincial Hospital of Traditional Chinese Medicin;0. Gansu Provincial Hospital of Traditional Chinese Medicin;1. Henan Rheumatism Hospita;2. Henan Provincial Hospital of Traditional Chinese Medicin;3. Wuhan City Hospital of Traditional Chinese Medicin;4. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Science) |
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| Abstract: | WANG Jian;GONG Xun;TANG Xiaopo;LIU Hongxiao;LIU Jian;HE Dongyi;ZHANG Junli;LI Zhenbin;HUANG Qingchun;WANG Xinchang;WU Qingjun;FANG Yongfei;WANG Yue;CHEN Shi;JIANG Hong;GAO Mingli;LIU Wei;LIU Ying;LI Zeguang;ZHAO Zhongwen;WANG Chengwu;LIU Weichao;WANG Haidong;LOU Yuqian;MENG Qingliang;RUAN Chongjie;XlE Yanming;JIANG Quan(Guang＇anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053;The First Affiliated Hospital of Anhui University of Chinese Medicine;Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine;The Fifth Hospital of Xi＇an;Bethune International Peace Hospital;Guangdong Proyincial Hospital Of Traditional Chinese Medicine;The Second Affiliated Hospital of Zhejiang University of Chinese Medicine;Peking Union Medical College Hospital;Affiliated Hospital of the Third Military Medical University of the Chinese People＇s Liberation Army;6. First Affiliated Hospital, Heilongjiang University of Chinese Medicin;7. The Second People＇s Hospital of Fujian Provinc;8. The First Affiliated Hospital of Changehun University of Traditional Chinese Medicin;9. Yunnan Provincial Hospital of Traditional Chinese Medicin;0. Gansu Provincial Hospital of Traditional Chinese Medicin;1. Henan Rheumatism Hospita;2. Henan Provincial Hospital of Traditional Chinese Medicin;3. Wuhan City Hospital of Traditional Chinese Medicin;4. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Science) |
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| Keywords: | rheumatoid arthritis syndrome distribution dampness heat obstruction syndrome cross-sectional survey |
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