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Paraneoplastic pemphigus presenting as erythrodermic lichenoid dermatitis with concomitant features of pemphigus foliaceus |
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| Authors: | Fukumoto Takaya Shiroyama Yoshimi Niizeki Hironori Kobayashi Nobuhiko Asada Hideo Ishii Norito Hashimoto Takashi Miyagawa Sachiko |
| Affiliation: | Department of Dermatology, Nara Medical University School of Medicine, Nara, Japan. tfukumot@naramed-u.ac.jp |
| Abstract: | We describe a patient with paraneoplastic pemphigus who presented with erythrodermic lichenoid dermatitis, later developing blisters of pemphigus foliaceus type and oral erosive lesions. In addition to antibodies against the plakin family proteins, the patient's serum was positive for anti-desmoglein 1 antibodies without coexisting anti-desmoglein 3 activities by enzyme-linked immunosorbent assay, which is a very rare autoantibody profile in paraneoplastic pemphigus. |
| Keywords: | desmoglein 1 erythroderma lichenoid dermatitis paraneoplastic pemphigus pemphigus foliaceus. |
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