| 大肠癌组织及转移瘤的微血管计数 |
| |
| 引用本文： | 王亚旭,李增鹏. 大肠癌组织及转移瘤的微血管计数[J]. 中国普通外科杂志, 2001, 10(3): 241-243 |
| |
| 作者姓名： | 王亚旭 李增鹏 |
| |
| 作者单位： | 1. 三军医大学大坪医院普外科,
2. 第三军医大学大坪医院病理科, |
| |
| 摘 要： | 目的研究大肠癌组织与转移瘤的血管生成情况及其与肿瘤转移和预后的关系。方法应用免疫组化法，研究了15例有淋巴结和肝转移的大肠癌、20例无转移的大肠癌和正常结肠粘膜的石蜡包埋组织的微血管计数。结果平均血管密度(MVD)值大肠癌组织(56.17±8.31)和肝转移瘤(94.26±10.46)明显高于正常粘膜(21.36±5.20)(P均<0.01)，发生转移的大肠癌组织的MVD值(90.27±7.16)明显高于未发生转移的大肠癌组织(56.17±8.31)(P<0.01)。结论大肠癌的MVD值可以作为判断肿瘤转移和预后的参考指标。
|
| 关 键 词： | 病理学 血液供给 淋巴转移 微血管 大肠癌 |
| 文章编号： | 1005-6947(2001)03-0241-03 |
| 修稿时间： | 2000-11-19 |
Microvessel quantitationin colorectal tumors and metastasis |
| |
| WANG Ya-xu,LI Zeng-peng. Microvessel quantitationin colorectal tumors and metastasis[J]. Chinese Journal of General Surgery, 2001, 10(3): 241-243 |
| |
| Authors: | WANG Ya-xu LI Zeng-peng |
| |
| Affiliation: | WANG Ya xu 1,LI Zeng peng 2 |
| |
| Abstract: | Objective To study the angiogenesis of colorectal tumors and the metastasis, and the relationsthip between microvessel with metastasis. Methods 15 colorectal tumors with lymph node and liver metastasis, 20 colorectal tumors without metastasis, and 20 nomal mucosa were studied imunohistochemically for microvessels quantitation. Results The mean vascular density (MVD) in colorectal tumors (56.17±8.31) and liver metastasis (94.26±10.46) were significantly higher than that in nomal mucosa (21.36±5.20)(P<0.01), the MVD in colorectal with metastas (90.27±7.16) were significantly higher than that in colorectal without metastasis (51.67±8.31) (P<0.01). Conclusions MVD can be used to evaluat the metastasis and as a prognostic factor in colorectal cancer patients. |
| |
| Keywords: | COLORECTAL NEOPLASMS/pathol ?COLORECTAL NEOPLASMS/blood sapply LIVER NEOPLASMS/second LYMPHATIC METASTASIS MICROVESSEL |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
