| MSCT灌注扫描时间-密度曲线鉴别诊断鼻咽癌放疗后局部复发与纤维化 |
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| 引用本文： | 金观桥,苏丹柯,丁玲,谢东,刘丽东,朱旭娜,赖少侣,黄向阳.MSCT灌注扫描时间-密度曲线鉴别诊断鼻咽癌放疗后局部复发与纤维化[J].中国医学影像技术,2010,26(12):2267-2270. |
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| 作者姓名： | 金观桥 苏丹柯 丁玲 谢东 刘丽东 朱旭娜 赖少侣 黄向阳 |
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| 作者单位： | 广西医科大学附属肿瘤医院影像中心,广西,南宁,530021 |
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| 摘 要： | 目的 通过MSCT灌注扫描时间-密度曲线,探讨鼻咽癌放疗后局部复发与纤维化的鉴别要点。方法 53例鼻咽癌放疗后患者按照病理结果分为鼻咽癌放疗后局部复发组和纤维化组,行MSCT灌注扫描,将获得的340幅连续图像传入GE AW 4.2工作站,利用Perfusion 3软件行后处理,软件自动生成时间-密度曲线,在曲线上计算峰值及达峰时间,并进行统计学分析。结果 鼻咽部放疗后局部复发组与纤维化组的峰值、达峰时间差异有统计学意义;鼻咽癌放疗后局部复发组和纤维化组拟合后的时间-密度曲线构成比差异有统计学意义,曲线类型分为 "速升速降"型(Ⅰ型)、"速升缓降"型(Ⅱ型)、"缓升缓降"型(Ⅲ型)和"平坦"型(Ⅳ型)。联合Ⅰ和Ⅱ型拟合后的时间-密度曲线对鼻咽癌复发诊断敏感度和特异度分别为89.29%、88.00%,阳性预测值、阴性预测值分别为89.29%、88.00%。结论 鼻咽癌放疗后复发与纤维化的MSCT灌注扫描的时间-密度曲线的峰值、达峰时间以及类型不同,有助于鉴别诊断。
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| 关 键 词： | 体层摄影术 X线计算机 鼻咽肿瘤 时间-密度曲线 |
| 收稿时间： | 6/4/2010 12:00:00 AM |
| 修稿时间： | 9/7/2010 12:00:00 AM |
Differentiation between local recurrence and fibrosis in patients with post radiotherapy nasopharyngeal carcinoma by time-density curves of MSCT perfusion imaging |
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| JIN Guan-qiao,SU Dan-ke,DING Ling,XIE Dong,LIU Li-dong,ZHU Xu-n,LAI Shao-lv and HUANG Xiang-yang.Differentiation between local recurrence and fibrosis in patients with post radiotherapy nasopharyngeal carcinoma by time-density curves of MSCT perfusion imaging[J].Chinese Journal of Medical Imaging Technology,2010,26(12):2267-2270. |
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| Authors: | JIN Guan-qiao SU Dan-ke DING Ling XIE Dong LIU Li-dong ZHU Xu-n LAI Shao-lv and HUANG Xiang-yang |
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| Institution: | Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China;Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China;Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China;Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China;Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China;Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China;Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China;Imaging Center, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China |
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| Abstract: | |
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| Keywords: | Tomography X-ray computed Nasopharyngeal neoplasms Time-density curve |
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