发作性运动诱发性运动障碍11例临床分析

目的 总结发作性运动诱发性运动障碍的临床特征，并对其进行分析。方法 观察分析11例PKD临床特征，影像学，脑电图等特点。结果 11例患者发病年龄7-21岁，平均10．3岁。发作前均有明显的诱发因素，临床表现为一侧或双侧肢体不自主的扭曲，舞蹈样动作，持续数秒钟，意识清楚，影像学及体检无异常，脑电图1例异常，卡马西平治疗效果佳。结论 PKD是发作性运动障碍中的一类疾病，属于离子通道病，对抗癫痫药物疗效好。

Clinical study on 11 case of paroxysmal kinesigenic dyskinesias

Objective] To investigate the clinical characteristics of paroxysmal kinesigenic dyskinesias(PKD).Metheds] 11 patients with PKD were analyzed including the clinical data,imaging and electroencephalograms(EEG).Result] 11 patients with PKD,the age of onset ranged from 7 to 21 years,average 10.3 years.Evident inducing factors were found before PKD and its clinical characteristics were periodic involuntary movement of one side or both sides of the limbs,trunks which lasted usually several seconds,without loss of consciousness,all the laboratory tests showed no abnormality except for 1 case had abnormal EEG findings,and carbamazepine was effective to patients with PKD.Conclusion] PKD is one kind of paroxysmal dyskinesia,and belonged to channelopathy.Antiepileptic drugs are effective to PKD.