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吸烟对ED患者血管内皮功能影响的研究
引用本文:Yao FJ,Huang YP,Lin H,Liu DH,Fan R,Liu YQ,Lu K,Deng CH,Sun XZ. 吸烟对ED患者血管内皮功能影响的研究[J]. 中华男科学杂志, 2011, 17(5): 414-417
作者姓名:Yao FJ  Huang YP  Lin H  Liu DH  Fan R  Liu YQ  Lu K  Deng CH  Sun XZ
作者单位:1. 中山大学附属第一医院,超声科,广东,广州,510080
2. 中山大学附属第一医院,泌尿外科,广东,广州,510080
摘    要:目的:探讨吸烟对无其他心血管危险因素的年轻勃起功能障碍(ED)患者内皮功能的影响。方法:我院泌尿外科门诊和住院ED患者,其中吸烟组21例,非吸烟组48例,健康对照组16例,所有受试者均进行肱动脉血流介导的内径扩张功能(FMD)的测定,同时检测其血压、血糖、血脂等指标。结果:与健康对照组相比,ED组患者FMD明显降低,而ED组中吸烟组FMD又明显低于非吸烟组[吸烟组(6.0±0.8)%,非吸烟组(9.7±2.5)%,对照组(14.0±2.5)%],组间差异均有统计学意义(P<0.05)。结论:ED患者存在内皮功能障碍,吸烟进一步加重ED患者内皮功能的损害。

关 键 词:阴茎勃起功能障碍  吸烟  血流介导的内皮依赖性舒张功能

Smoking impairs endothelial function in ED patients
Yao Feng-juan,Huang Yan-ping,Lin Hong,Liu Dong-hong,Fan Rui,Liu Yan-qiu,Lu Kun,Deng Chun-hua,Sun Xiang-zhou. Smoking impairs endothelial function in ED patients[J]. National journal of andrology, 2011, 17(5): 414-417
Authors:Yao Feng-juan  Huang Yan-ping  Lin Hong  Liu Dong-hong  Fan Rui  Liu Yan-qiu  Lu Kun  Deng Chun-hua  Sun Xiang-zhou
Affiliation:Department of Ultrasound, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
Abstract:Objective: To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease.Methods: This study included 69 ED patients(21 smokers and 48 non-smokers) and 16 age-matched normal healthy controls.All underwent measurement of brachial artery flow-mediated vasodilation(FMD) and examinations of blood pressure,cholesterol,triglycerides and glucose.Results: Brachial artery FMD was remarkably decreased in the ED patients,even more significantly in the smokers([6.0±0.8] %) than in the non-smokers([9.7±2.5] %)(P0.05),as compared with that in the normal healthy controls([14.0±2.5] %,P0.05).Conclusion: Endothelial function is impaired in ED patients,and is further damaged by smoking.
Keywords:erectile dysfunction  smoking  brachial artery flow-mediated vasodilation
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