| 吸烟对ED患者血管内皮功能影响的研究 |
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| 作者姓名： | Yao FJ Huang YP Lin H Liu DH Fan R Liu YQ Lu K Deng CH Sun XZ |
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| 作者单位： | 1. 中山大学附属第一医院,超声科,广东,广州,510080
2. 中山大学附属第一医院,泌尿外科,广东,广州,510080 |
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| 摘 要： | 目的:探讨吸烟对无其他心血管危险因素的年轻勃起功能障碍(ED)患者内皮功能的影响。方法:我院泌尿外科门诊和住院ED患者,其中吸烟组21例,非吸烟组48例,健康对照组16例,所有受试者均进行肱动脉血流介导的内径扩张功能(FMD)的测定,同时检测其血压、血糖、血脂等指标。结果:与健康对照组相比,ED组患者FMD明显降低,而ED组中吸烟组FMD又明显低于非吸烟组吸烟组(6.0±0.8)%,非吸烟组(9.7±2.5)%,对照组(14.0±2.5)%],组间差异均有统计学意义(P<0.05)。结论:ED患者存在内皮功能障碍,吸烟进一步加重ED患者内皮功能的损害。
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| 关 键 词： | 阴茎勃起功能障碍 吸烟 血流介导的内皮依赖性舒张功能 |
Smoking impairs endothelial function in ED patients |
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| Yao FJ,Huang YP,Lin H,Liu DH,Fan R,Liu YQ,Lu K,Deng CH,Sun XZ.Smoking impairs endothelial function in ED patients[J].National Journal of Andrology,2011,17(5):414-417. |
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| Authors: | Yao Feng-juan Huang Yan-ping Lin Hong Liu Dong-hong Fan Rui Liu Yan-qiu Lu Kun Deng Chun-hua Sun Xiang-zhou |
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| Institution: | Department of Ultrasound, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China. |
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| Abstract: | Objective： To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease.Methods： This study included 69 ED patients（21 smokers and 48 non-smokers） and 16 age-matched normal healthy controls.All underwent measurement of brachial artery flow-mediated vasodilation（FMD） and examinations of blood pressure,cholesterol,triglycerides and glucose.Results： Brachial artery FMD was remarkably decreased in the ED patients,even more significantly in the smokers（6.0±0.8] %） than in the non-smokers（9.7±2.5] %）（P0.05）,as compared with that in the normal healthy controls（14.0±2.5] %,P0.05）.Conclusion： Endothelial function is impaired in ED patients,and is further damaged by smoking. |
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| Keywords: | erectile dysfunction smoking brachial artery flow-mediated vasodilation |
| 本文献已被 维普 万方数据 PubMed 等数据库收录！ |
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