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2型糖尿病并发冠心病与基质金属蛋白酶9水平的关系
引用本文:何茜,徐淑静,时立新,杨天和,谭洪文. 2型糖尿病并发冠心病与基质金属蛋白酶9水平的关系[J]. 中华内分泌代谢杂志, 2011, 27(10). DOI: 10.3760/cma.j.issn.1000-6699.2011.10.007
作者姓名:何茜  徐淑静  时立新  杨天和  谭洪文
作者单位:1. 贵州省人民医院内分泌科
2. 550004,贵阳医学院附属医院内分泌科
3. 贵州省人民医院心内科
基金项目:贵州省卫生厅科学技术基金
摘    要:根据冠状动脉造影结果将患者分为2型糖尿病组27例、冠心病组30例、2型糖尿病合并冠心病组32例,并选取32名正常对照者,分别测定血清基质金属蛋白酶9浓度和其他临床及实验室生化指标.结果显示,基质金属蛋白酶9在2型糖尿病并发冠心病中可能起一定作用.

关 键 词:基质金属蛋白酶9  糖尿病,2型  冠心病

Relationship between serum matrix metalloproteinase-9 level and coronary heart disease in type 2 diabetic patients
HE Xi,XU Shu-jing,SHI Li-xin,YANG Tian-he,TAN Hong-wen. Relationship between serum matrix metalloproteinase-9 level and coronary heart disease in type 2 diabetic patients[J]. Chinese Journal of Endocrinology and Metabolism, 2011, 27(10). DOI: 10.3760/cma.j.issn.1000-6699.2011.10.007
Authors:HE Xi  XU Shu-jing  SHI Li-xin  YANG Tian-he  TAN Hong-wen
Abstract:Twenty-seven cases of simple type 2 diabetes mellitus,30 cases of coronary heart disease,and 32 cases of type 2 diabetes with coronary heart disease were enrolled in this study according to the results of coronary angiography.Meanwhile,32 healthy subjects were taken as a control group.The serum matrix metalloproteinase-9 (MMP-9) and other clinical and laboratory parameters were determined.The results showed that serum MMP-9 may play a minor role in the progression of coronary heart disease in type 2 diabetic patients.
Keywords:Matrix metalloproteinase-9  Diabetes mellitus,type 2  Coronary heart disease
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