| Gastrointestinal stromal tumour of the rectum： Report of a case and review of literature |
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| 引用本文： | Grassi N,Cipolla C,Torcivia A,Mandala S,Graceffa G,Bottino A,Latteri F. Gastrointestinal stromal tumour of the rectum： Report of a case and review of literature[J]. World journal of gastroenterology : WJG, 2008, 14(8): 1302-1304. DOI: 10.3748/wjg.14.1302 |
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| 作者姓名： | Grassi N Cipolla C Torcivia A Mandala S Graceffa G Bottino A Latteri F |
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| 作者单位： | Department of Oncology Division of General and Oncological Surgery University of Palermo Via del Vespro 129 Palermo 90127 Italy,Department of Oncology Division of General and Oncological Surgery University of Palermo Via del Vespro 129 Palermo 90127 Italy,Department of Oncology Division of General and Oncological Surgery University of Palermo Via del Vespro 129 Palermo 90127 Italy,Department of Oncology Division of General and Oncological Surgery University of Palermo Via del Vespro 129 Palermo 90127 Italy,Department of Oncology Division of General and Oncological Surgery University of Palermo Via del Vespro 129 Palermo 90127 Italy,Department of Oncology Division of General and Oncological Surgery University of Palermo Via del Vespro 129 Palermo 90127 Italy,Department of Oncology Division of General and Oncological Surgery University of Palermo Via del Vespro 129 Palermo 90127 Italy |
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| 摘 要： | Gastrointestinal stromal tumour （GIST） is a rare tumour of the gastrointestinal tract which does not generally originate in the rectum. The authors describe a case of a 70-year-old man who underwent an anterior resection of the rectum for a low-risk GIST. The patient was not given adjuvant chemotherapy with imatinib and is still disease-free 30 mo after surgery. The authors conclude that although rectal GIST is extremely uncommon, it should be included in differential diagnosis when a tumour in the rectum is detected. Biopsy of the tumour is essential, since this makes it possible to reach a sure preoperative diagnosis based on the immunohistological features of the CDl17 and CD34. Although complete surgical resection with negative tumour margins is the principal curative procedure for primary and nonmetastatic tumours, further studies are still needed for the determination of the most effective treatment strategy for patients with rectal GIST.
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| 关 键 词： | 直肠肿瘤 胃肠道肿瘤 诊断 治疗 |
| 收稿时间： | 2007-11-01 |
Gastrointestinal stromal tumour of the rectum: report of a case and review of literature |
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| Grassi Nello,Cipolla Calogero,Torcivia Adriana,Mandala Stefano,Graceffa Giuseppa,Bottino Alessandro,Latteri Federica. Gastrointestinal stromal tumour of the rectum: report of a case and review of literature[J]. World journal of gastroenterology : WJG, 2008, 14(8): 1302-1304. DOI: 10.3748/wjg.14.1302 |
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| Authors: | Grassi Nello Cipolla Calogero Torcivia Adriana Mandala Stefano Graceffa Giuseppa Bottino Alessandro Latteri Federica |
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| Affiliation: | Department of Oncology,Division of General and Oncological Surgery,University of Palermo,Via dei Vespro 129,Palermo 90127,Italy |
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| Abstract: | Gastrointestinal stromal tumour (GIST) is a rare tumour of the gastrointestinal tract which does not generally originate in the rectum. The authors describe a case of a 70-year-old man who underwent an anterior resection of the rectum for a low-risk GIST. The patient was not given adjuvant chemotherapy with imatinib and is still disease-free 30 mo after surgery. The authors conclude that although rectal GIST is extremely uncommon, It should be included in differential diagnosis when a tumour in the rectum is detected. Biopsy of the tumour is essential, since this makes it possible to reach a sure preoperative diagnosis based on the immunohistological features of the CDl17 and CD34.Although complete surgical resection with negative tumour margins is the principal curative procedure for primary and nonmetastatic tumours, further studies are still needed for the determination of the most effective treatment strategy for patients with rectal GIST. |
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| Keywords: | Rectal Gastrointestinal stromal tumour Diagnosis Treatment Surgery rectum tumour Gastrointestinal literature review case studies determination effective treatment strategy patients complete surgical resection negative principal procedure primary reach sure |
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