Identification of herpes simplex viruses by automated profile analysis of viral proteins |
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Authors: | J D Connor P Walpita |
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Affiliation: | Dept. of Pediatrics, University of California, San Diego, La Jolla, CA, U.S.A. |
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Abstract: | In this report we describe a computerized virus identification system based upon the fact that viral proteins, separated by one-dimensional (ID) SDS-PAGE have unique banding patterns (protein profiles). Fifty-eight clinical strains of herpes simplex virus (HSV) were correctly identified by comparing their protein profiles with reference profiles of HSV, other viruses and uninfected cell cultures stored in a computer data base. |
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