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THE EFFECT OF RETINOIC ACID ON CELL MEMBRANE AND METASTATIC ABILITY OF MOUSE FORESTOMACH CARCINOMA C
引用本文:于晓妉,赵雪梅,高进.THE EFFECT OF RETINOIC ACID ON CELL MEMBRANE AND METASTATIC ABILITY OF MOUSE FORESTOMACH CARCINOMA C[J].中国癌症研究,1996,8(2):91-94.
作者姓名:于晓妉  赵雪梅  高进
作者单位:Institute of Basic Medical Sciences. Chinese Academy of,Medical Sciences.School of Basic Medicine,Peking Union Medical Coliege. Beijing 100005
摘    要:THEEFFECTOFRETINOICACIDONCELLMEMBRANEANDMETASTATICABILITYOFMOUSEFORESTOMACHCARCINOMACELLYuXiaodan于晓;ZhaoXuemei赵雪梅;GaoJin高进(In...

修稿时间:9 February 1996

The effect of retinoic acid on cell membrane and metastatic ability of mouse forestomach carcinoma cell
Yu Xiaodan,Zhao Xuemei,Gao Jin.The effect of retinoic acid on cell membrane and metastatic ability of mouse forestomach carcinoma cell[J].Chinese Journal of Cancer Research,1996,8(2):91-94.
Authors:Yu Xiaodan  Zhao Xuemei  Gao Jin
Institution:(1) Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences. School of Basic Medicine, Peking Union Medical College, 100005 Beijing
Abstract:We studied the effect of all-trans-retinoic acid (RA)on the expression of several surface lectin receptors and cell membrane fluidity of mouse forestomach carcinoma cell line (MFC) in vitro. The results showed that cells treated with RA manifested decreased expression of lectin receptors, increased memhrane fluidity and reduced spontaneous metastasis. These results suggest that the effect of RA on tumor cell membrane may be one of the mechanisms involved in the alternation of cell metastatic phenotype.
Keywords:Retinoic acid  Cell membrane fluidity  Tumor metastasis
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