| 结肠癌复发因素的多元回归分析 |
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| 引用本文： | 杜寒松,王国斌,秦青平,夏玉春,陶荣盛,司徒光伟. 结肠癌复发因素的多元回归分析[J]. 华中科技大学学报(医学版), 2004, 33(3): 343-346 |
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| 作者姓名： | 杜寒松 王国斌 秦青平 夏玉春 陶荣盛 司徒光伟 |
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| 作者单位： | 1. 华中科技大学同济医学院附属协和医院普外科,武汉,430022
2. 武汉钢铁公司总医院普外科,武汉,430081 |
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| 基金项目： | 湖北省自然科学基金资助项目(No.2003ABA151) |
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| 摘 要： | 目的 探讨影响结肠癌患者长期生存的独立预后因素。方法 采用Cox比例风险模型对可能影响结肠癌患者预后的指标 ,进行多因素回归分析。结果 单因素分析显示Dukes分期、梗阻、生长方式、化疗与结肠癌患者术后复发率显著相关 (均为P <0 0 5 )。Cox多因素回归分析显示 ,按作用强度Dukes分期、梗阻、术后化疗依次为影响结肠癌患者根治术后复发的因素。结论 Dukes分期、梗阻、术后化疗为结肠癌患者根治术后的独立复发因素。
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| 关 键 词： | 结肠肿瘤 肿瘤复发 Cox回归分析 |
| 修稿时间： | 2003-04-14 |
Cox Multivariate Regression Analysis of Recurrence Factors for Colon Cancer |
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| Abstract: | Objective To determine the independent prognostic factors influencing long-term survival rate of the patients with colon cancer after curative resection.Methods Univariate and Cox multivariate regression analysis was performed on 201 patients who underwent curative resection for colon cancer. Ten factors contributing to the recurrence rate were analyzed. Results Dukes stages, obstruction, postoperative chemotherapy, growth manner of the tumor were significantly correlated with recurrence rate by univariate analysis (P<0.05). Multivariate analysis revealed that the Dukes stages, obstruction, postoperation chemotherapy were significant factors for recurrence rate of colon cancer. Conclusion Dukes stages, obstruction and postoperation chemotherapy are independent prognostic factors for colon cancer. |
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| Keywords: | colon neoplasms neoplasm recurrence Cox regression analysis |
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