22例外阴原发性恶性肿瘤临床病理分析

目的 分析外阴原发性恶性肿瘤的临床和病理特征。方法 收集外阴原发性恶性肿瘤22例的临床和病理资料，其中8例用免疫组化方法作了HPV染色。结果 22例中鳞状细胞癌13例、疣状癌4例、湿疣样癌1例、腺癌1例、鲍温样丘疹病恶变1例、恶性黑色素瘤1例、派杰病1例。结论 原发性外阴癌组织类型多样，其中部分与HPV感染有关，湿疣样癌需与疣状癌鉴别。

A Clinicopathological Analysis of 22 Cases with Pri4ary Malignancy of Vulva

Objective To analyze the clinicopathological characteristics of malignancies of vulva. Methods The clinical and pathological materials of 22 such cases were collected, among which 8 cases were detected with HPV. Results In 22 cases, 13 cases were squamous cell carcinoma, 4 cases of verrucous carcinoma, 1 case of warty carcinoma, 1 case of adenocarcinoma. Bowenoid papulosis with malignant transformation 1 case,malignant melanoma 1 case,and Paget's disease 1 case. Conclusion The histological types of primary malignant neoplasms are diversified, some of which are related with HPV infection and warty carcinoma should be differentiated with verrucous carcinoma.