| 艾素联合奈达铂治疗中晚期非小细胞肺癌的临床研究 |
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| 引用本文： | 孙贵富. 艾素联合奈达铂治疗中晚期非小细胞肺癌的临床研究[J]. 现代肿瘤医学, 2008, 16(11) |
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| 作者姓名： | 孙贵富 |
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| 作者单位： | 沐阳县人民医院肿瘤科,江苏,宿迁,223600 |
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| 摘 要： | 目的:观察艾素(Docetaxel TAX)联合奈达铂(Nedapltin NDP)治疗中晚期非小细胞肺癌(NSCLC)的疗效及不良反应。方法:入组36例中晚期非小细胞肺癌患者。TAX 60mg/m2,静滴1小时,第一天;NDP 80-100mg/m2,第2天。每3周为1个周期。结果:入组36例均可评价疗效,CR 1例,PR15例,SD13例,PD7例,RR为44.44%(16/36)。结论:艾素联合奈达铂治疗中晚期非小细胞肺癌的疗效较好,副作用可耐受,可作为治疗中晚期非小细胞肺癌一线或二线化疗方案。
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| 关 键 词： | 艾素 奈达铂 非小细胞肺癌 化学治疗 |
Clinical study of docetaxel plus nedapltin in the treatment of advanced non-small cell lung cancer |
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| SUN Gui-fu. Clinical study of docetaxel plus nedapltin in the treatment of advanced non-small cell lung cancer[J]. Journal of Modern Oncology, 2008, 16(11) |
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| Authors: | SUN Gui-fu |
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| Abstract: | Objective:To observe the therapeutic effect and toxicity of docetaxel plus nedapltin in advanced non-small cell lung cancer(NSCLC).Methods: All 36 patients with advanced NSCLC were treated with docetaxel 60mg/m2 iv infusion 1 hour d1 and NDP 80-100mg/m2 iv infusion d2,the schedule was repeated every 3 weeks.Results: The objective response might be evaluated in all cases.There was 1 case with CR,15 PR,13 SD,7 PD,RR(CR PR) 44.44%(16/36).Conclusion: The TAX plus NDP regimen is effective in the treatment of advanced NSCLC with better tolerence,it may be used as the first and second line chemotherapy. |
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| Keywords: | docetaxel nedapltin non-small cell lung cancer chemotherapy |
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