| 西洋参茎叶皂甙对大鼠冠脉前降支损伤心肌FFA和LDH的影响 |
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| 引用本文： | 金毅,吕忠智. 西洋参茎叶皂甙对大鼠冠脉前降支损伤心肌FFA和LDH的影响[J]. 吉林大学学报(医学版), 1992, 0(2) |
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| 作者姓名： | 金毅 吕忠智 |
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| 作者单位： | 吉林省中医中药研究院中药研究所(金毅)，白求恩医科大学基础医学院药理教研室(吕忠智) |
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| 摘 要： | 应用大鼠冠状动脉前降支损伤心肌模型,观察西洋参茎叶皂甙(panax quinque-folium saponins,PQS)对大鼠心肌游离脂肪酸(FFA)含量和乳酸脱氢酶(LDH)活性的影响,结果提示PQS抗心肌缺血作用与其降低心肌FFA含量和提高LDH活性有密切关系。
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| 关 键 词： | 西洋参茎叶皂甙 游离脂肪酸 乳酸脱氢酶 |
EFFECT OF PQS ON FFA AND LDH IN RAT MYOC RDIUMDAMAGED BY INJURING THE LEFT ANTERICRDESCENDING CORONARY ARTERY |
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| Jin Yi,Lu Zhongzhi. EFFECT OF PQS ON FFA AND LDH IN RAT MYOC RDIUMDAMAGED BY INJURING THE LEFT ANTERICRDESCENDING CORONARY ARTERY[J]. Journal of Jilin University: Med Ed, 1992, 0(2) |
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| Authors: | Jin Yi Lu Zhongzhi |
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| Affiliation: | Department of Pharmacology |
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| Abstract: | The effect of PQS on HA and LDH in rat myocardium damaged by coagulating the left anterior descending coronary artery was observed . The content of FFA was decreased and the activity of LDH was enhanced in the damaged myocardium in rats pretreated with PQS (90. 180mg/kg i. p.) What we observed suggests that PQS has an action to protect the myocardium, and its anti-ischemic action is closely related to a decrease in FFA level and an elevation of the activity of LDH. |
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| Keywords: | Panax quinquefolium saponins Free fatty acid Lactate dehydrogenase |
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