Effects of granulocyte-macrophage colony-stimulating factor produced by intestinal epithelial cells on functional activity of hemopoietic stem cells |
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| Authors: | Sennikov S V Temchura V V Trufakin V A Kozlov V A |
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| Affiliation: | (1) Siberian Division of the Russian Academy of Medical Sciences, Laboratory of Hemopoiesis Regulation, Institute of Clinical Immunology, Russia;(2) Siberian Division of the Russian Academy of Medical Sciences, Institute of Physiology, Novosibirsk |
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| Abstract: | The population of epithelial cells in the small intestine includes precursor cells of hemopoiesis possessing the ability to form splenic colonies on day 8. Intestinal epithelial cells stimulates proliferative and colony-forming activity of hemopoietic stem cells by producing granulocyte-macrophage colony-stimulating factor. |
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| Keywords: | hemopoietic stem cell intestinal epithelial cells granulocyte-macrophage colony-stimulating factor |
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