| Abstract: | The investigation was undertaken to estimate the degree of endogenous intoxication (EI) in septic infants, by studying the levels of circulating immune complexes (CIC) and leukocyte intoxication index (LII). A clinical trial was conducted in 46 patients with septic infants aged 1 month to 1.5 years. According to clinical and laboratory parameters, the author identified 3 grades of EI, which were directly related to the patient's condition. Despite clinical resolution, the levels of CIC and LII significantly remained at the high baseline level in 18% of the patient, which created conditions for developing complications and recurrences and suggested that the pathological process was incomplete. Therefore it is recommended to keep in mind these indicators in predicting sepsis and they may be extensively used in the practical health system. |
