| 窒息新生儿血胱抑素C、尿微量蛋白的测定及其意义 |
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| 引用本文： | 马素丽,王燕,王佳.窒息新生儿血胱抑素C、尿微量蛋白的测定及其意义[J].中国误诊学杂志,2011,11(32):7826-7827. |
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| 作者姓名： | 马素丽 王燕 王佳 |
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| 作者单位： | 1. 河南省漯河市中心医院(漯河医专一附院)儿科 462000
2. 河南省漯河市中心医院(漯河医专一附院)药剂科 462000 |
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| 摘 要： | 目的 探讨血胱抑素C、尿微量蛋白对窒息新生儿肾功能损害的诊断价值.方法 选取新生儿窒息的新生儿80例为窒息组,按照新生儿窒息诊断标准又将其分为轻度组(45例)和窒息组(35例).选取无肾功能损害的非窒息新生儿32例为对照组.用酶联免疫吸附法测定患儿日龄3d内的血尿素氮(BUN)、血肌酐(SCr)及血胱抑素(Cys C)尿微量蛋白α1微球蛋白(α1-M)、清蛋白(Alb)、β2微球蛋白(β2-M)的水平,比较各组间各指标的差异.结果 窒息组血Cys C、SCr、BUN水平较对照组增高(P＜0.05),尿α1-M、Alb、β2-M较对照组显著增高,重度组升高更明显(P＜0.01).结论 用血Cys C和尿微量蛋白联合检测对临床肾功能的监测有重要意义.
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| 关 键 词： | 半胱氨酸蛋白酶抑制剂 血液 蛋白尿 代谢 |
Determination and significances of serum cystatin C and urine microprotein in asphyxia of newborn |
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| MA Su-li,WANG Yan,WANG Jia.Determination and significances of serum cystatin C and urine microprotein in asphyxia of newborn[J].Chinese Journal of Misdiagnostics,2011,11(32):7826-7827. |
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| Authors: | MA Su-li WANG Yan WANG Jia |
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| Institution: | MA Su-li,WANG Yan,WANG Jia Department of Pharmacy,Center Hospital of Luohe City,Luohe 462000,China |
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| Abstract: | Objective To evaluate the diagnostic value of serum cystatin C(Cys C) and urine microprotein for renal function impairment in asphyxia of newborn.Methods The serum Cys C,BUN and serum creatinine concentrations were measured by enzyme linked immunosorbent assay(ELISA) in 80 cases of asphyxia newborns(45 cases were mild asphyxia of newborn and 35 cases were severe asphyxia of newborn) wihtin 3 days after their birth.32 cases without perinatal asphyxia or other factors which could result in renal function impa... |
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| Keywords: | Cysteine Proteinase Inhibitors/Blood Proteinuria/metabolism |
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