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68Ga-成纤维细胞激活蛋白抑制剂PET/CT显像指南
引用本文:陈跃,邱琳,石洪成,程登峰,孙龙,霍力,兰晓莉,徐浩,赵军,宋少莉,庞华,朱华,李亚明.68Ga-成纤维细胞激活蛋白抑制剂PET/CT显像指南[J].中国医学影像技术,2022,38(6):801-806.
作者姓名:陈跃  邱琳  石洪成  程登峰  孙龙  霍力  兰晓莉  徐浩  赵军  宋少莉  庞华  朱华  李亚明
作者单位:西南医科大学附属医院核医学科 核医学与分子影像四川省重点实验室 西南医科大学核医学研究所 四川省院士(专家)工作站, 四川 泸州 646000;复旦大学附属中山医院核医学科 复旦大学核医学研究所, 上海 200032;厦门大学附属第一医院核医学科, 福建 厦门 361003;中国医学科学院 北京协和医学院 北京协和医院核医学科, 北京 100730;华中科技大学同济医学院附属协和医院核医学科 湖北省分子影像重点实验室, 湖北 武汉 430022;暨南大学附属第一医院核医学科, 广东 广州 510630;同济大学附属东方医院 上海市东方医院核医学科, 上海 200120;复旦大学附属肿瘤医院核医学科 复旦大学上海医学院肿瘤学系, 上海 200032;重庆医科大学附属第一医院核医学科, 重庆 400042;北京大学肿瘤医院暨北京市肿瘤防治研究所核医学科, 恶性肿瘤发病机制及转化研究教育部重点实验室, 北京 100142;中国医科大学附属第一医院核医学科, 辽宁 沈阳 110001
基金项目:四川省卫生健康委员会医学科技重点研发项目(21ZD005)。
摘    要:68Ga-成纤维细胞激活蛋白抑制剂(FAPI) PET/CT用于各种肿瘤性疾病、感染、炎症性疾病诊治中,均涉及适应证、医务人员岗位职责、操作规范(包括病史采集、患者准备和检查注意事项、放射性药物制备、图像采集和图像分析)、报告、质量控制和显像过程中的辐射安全问题。本指南旨在为临床顺利开展68Ga-FAPI PET/CT检查,并在诊断报告中合理解释及标准化描述68Ga-FAPI PET/CT所见提供依据。

关 键 词:正电子发射断层显像  广谱显像剂  成纤维细胞激活蛋白  操作规范
收稿时间:2021/10/28 0:00:00
修稿时间:2022/5/18 0:00:00

Guideline for PET/CT imaging of 68Ga-fibroblast activation protein inhibitor
CHEN Yue,QIU Lin,SHI Hongcheng,CHENG Dengfeng,SUN Long,HUO Li,LAN Xiaoli,XU Hao,ZHAO Jun,SONG Shaoli,PANG Hu,ZHU Hu,LI Yaming.Guideline for PET/CT imaging of 68Ga-fibroblast activation protein inhibitor[J].Chinese Journal of Medical Imaging Technology,2022,38(6):801-806.
Authors:CHEN Yue  QIU Lin  SHI Hongcheng  CHENG Dengfeng  SUN Long  HUO Li  LAN Xiaoli  XU Hao  ZHAO Jun  SONG Shaoli  PANG Hu  ZHU Hu  LI Yaming
Institution:Department of Nuclear Medicine, the Affiliated Hospital of Southwest Medical University, Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Nuclear Medicine Institute of Southwest Medical University, Academician Workstation of Sichuan Province, Luzhou 646000, China;Department of Nuclear Medicine, Zhongshan Hospital Fudan University, Nuclear Medicine Institute of Fudan University, Shanghai 200032, China;Department of Nuclear Medicine, the First Hospital of Xiamen University, Xiamen 361003, China;Department of Nuclear Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China;Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Key Laboratory of Molecular Imaging, Wuhan 430022, China;Department of Nuclear Medicine, the First Affiliated Hospital of Jinan University, Guangzhou 510630, China;Department of Nuclear Medicine, East Hospital Affiliated to Tongji University, Shanghai Oriental Hospital, Shanghai 200120, China;Department of Nuclear Medicine, Fudan University Cancer Hospital, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Nuclear Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China;Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Beijing 100142, China; Department of Nuclear Medicine, the First Hospital of China Medical University, Shenyang 110001, China
Abstract:The application of 68Ga-fibroblast activation protein inhibitor (FAPI) PET/CT in diagnosing and treating various neoplastic diseases, infections and inflammatory diseases involves indications, responsibilities of medical personnel, examination specifications (including medical history collection, patient preparation and examination precautions, radiopharmaceutical preparation, image acquisition and image analysis), reporting, quality control and radiation safety issues during imaging process. This guideline aimed at providing appropriate operating specifications for successful clinical 68Ga-FAPI PET/CT examination and reasonable explanations and standard diagnostic reporting for 68Ga-FAPI PET/CT imaging.
Keywords:positron-emission tomography  broad-spectrum imaging agent  fibroblast activation protein  guideline
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