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Circulation of classical swine influenza virus in Europe between the wars? |
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| Authors: | Jeannette Lange Marco Groth Pumaree Kanrai Stephan Pleschka Christoph Scholtissek Ralf Dürrwald Matthias Platzer Andreas Sauerbrei Roland Zell |
| Institution: | 1. Department of Virology and Antiviral Therapy, Jena University Hospital, Friedrich Schiller University, Hans-Knoell-Str. 2, 07745, Jena, Germany 2. Genome Research, Fritz Lipmann Institute, Leibniz Institute of Age Research, Beutenbergstr. 11, 07745, Jena, Germany 3. Institute of Medical Virology, Justus Liebig University, Schubertstrasse 81, 35392, Giessen, Germany 4. IDT Biologika GmbH, Am Pharmapark, 06861, Dessau-Rosslau, Germany |
| Abstract: | The complete genomes of two swine influenza viruses from England were sequenced. Phylogenetic analysis revealed classical swine H1N1 viruses, one of which, A/swine/London, is closely related to virus strains of the early 1930s. Both strains are also antigenically related to A/swine/Iowa/15/1930, the strain originally isolated by Richard Shope. The source of A/swine/London is unknown, but its relationship to early classical swine influenza viruses suggests that the emergence of these viruses in Europe has to be antedated by 15-20 years. |
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