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Optical coherence tomography: a quantitative tool to screen for papilledema in craniosynostosis |
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| Authors: | Caroline Driessen Jordi Eveleens Isabel Bleyen Marie-Lise van Veelen Koen Joosten Irene Mathijssen |
| Affiliation: | 1. Department of Plastic, Reconstructive and Hand Surgery, Dutch Craniofacial Centre, Erasmus MC Sophia Children’s Hospital, Sk-1202, Post office box 2060, 3000, CB, Rotterdam, The Netherlands 2. Department of Ophthalmology, Erasmus MC Sophia Children’s Hospital, Rotterdam, The Netherlands 3. Department of Neurosurgery, Erasmus MC Sophia Children’s Hospital, Rotterdam, The Netherlands 4. Department of Pediatric Intensive Care, Erasmus MC Sophia Children’s Hospital, Rotterdam, The Netherlands |
| Abstract: | PurposeOur aim was to evaluate if optical coherence tomography (OCT) can be used as an alternative for fundoscopy to screen for increased intracranial pressure (ICP) in children with craniosynostosisMethodsWe performed a prospective cohort study at the Dutch Craniofacial Centre. We included 38 patients with nonsyndromic scaphocephaly and Crouzon’s syndrome aged 3–8 years old, in whom we scored complaints suggestive of increased ICP and performed fundoscopy and OCT. Main outcome measures total retinal thickness (TRT) which was measured on 58 OCT scans.ResultsForty-three percent of fundoscopies revealed pathologic changes of the papil in at least one eye. Retinal thickness was increased in patients with an abnormal fundoscopy as compared to patients with a normal papil (TRT p?p?Conclusions The current study demonstrates that OCT in children with craniosynostosis is feasible. It confirms that retinal thickness increases in case of papilledema. Given the quantitative character, OCT has a high potential as an alternative tool to screen for papilledema in craniosynostosis and other pediatric populations. |
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