| 系数倍率法与吸收度减法技术联用测定甲硝唑葡萄糖注射液中5-HMF的含量 |
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| 引用本文： | 黄颂,李枝瑞. 系数倍率法与吸收度减法技术联用测定甲硝唑葡萄糖注射液中5-HMF的含量[J]. 海峡药学, 2005, 17(4): 57-58 |
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| 作者姓名： | 黄颂 李枝瑞 |
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| 作者单位： | 宁德市药品检验所,宁德,352100;宁德市人民医院,宁德,352100 |
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| 摘 要： | 目的对甲硝唑葡萄糖注射液中5-HMF进行定量。方法应用系数倍率法与吸收度减法技术联用，不经分离在284nm、320nm波长处直接测定。结果消除了甲硝唑的吸收干扰，测得5-HMF在284nm波长处的吸收度。结论方法简单，结果准确。
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| 关 键 词： | 甲硝唑葡萄糖注射液 5-HMF 系数倍率法 吸收度减法技术 含量测定 |
| 文章编号： | 1006-3765（2005）04-0057-02 |
Quantitative Determination of 5-HMF in Metronidazole and Glucose Injection by Combined usage of K-ratio Spectrophotomerty and Absorbance Subtraction Technique |
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| HUANG Song,LI Zhi-duan. Quantitative Determination of 5-HMF in Metronidazole and Glucose Injection by Combined usage of K-ratio Spectrophotomerty and Absorbance Subtraction Technique[J]. Strait Pharmaceutical Journal, 2005, 17(4): 57-58 |
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| Authors: | HUANG Song LI Zhi-duan |
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| Abstract: | OBJECTIVE To determine the concentrations of 5-HMF in metronidazode and glucose injection. METHODS To perform by combined usage of K-ratio spectrophotomerty and absorbance subtraction technique technique at 284nm and 320nm without separating. RESULTS Presents the absorbace of 5-HMF at 284nm,the interference of metronidazole was eliminated. CONCLUSION The method is simple and accurate. |
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| Keywords: | Metronidazole and glucose injection 5-HMF, K-ratio spectrophotometry Absorbance subtraction technique~ Determination. |
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