| 大鼠肺内的降钙素基因相关肽 |
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| 引用本文： | 李春英,徐东,袁其晓,赵秋艳,吴璥,汤健. 大鼠肺内的降钙素基因相关肽[J]. 基础医学与临床, 1989, 0(5) |
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| 作者姓名： | 李春英 徐东 袁其晓 赵秋艳 吴璥 汤健 |
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| 作者单位： | 北京医科大学(李春英，徐东，袁其晓，赵秋艳)，中日友好医院(吴璥)，北京医科大学(汤健) |
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| 摘 要： | 应用特异的放射免疫测定和免疫组织化学方法,证明大鼠肺内存在降钙素基因相关肽(CGRP)。肺提取物的凝胶层析所获得的CGRP免疫活性峰表明大鼠肺内的CGRP是以单一分子形式存在的。实验对CGRP在肺内的分布进行了探讨。大鼠肺动脉离体实验表明CGRP有很强的肺动脉舒张作用。
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| 关 键 词： | 降钙素基因相关肽 肺 肺动脉 |
Calcitonin Gene-related Peptide in Rat Lung |
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| Li Chunying et al.. Calcitonin Gene-related Peptide in Rat Lung[J]. Basic Medical Sciences and Clinics, 1989, 0(5) |
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| Authors: | Li Chunying et al. |
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| Abstract: | The Present study demenstrated the existence of Calcitonin gene-related peptide (CGRP) in rat lung by using specific radioimmunoassay and immunohi-stochemistry methods. Gel filtration of pulmonary extracts showed one majer peak of CGRP immunoreactivity, indicating that there is only one monomole-cular form of CGRP in rat lung. The distribution of CGRP in various parts of rat lung was also investigated. In vitro experiment, it showed that CGRP has potent vasodilatine effect on rat pulmonary artery. |
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| Keywords: | Calcitonin gene-related peptide (CGRP) Lung Pulmonary artery |
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