| AUTOFLUORESCENCE EXCITED BY ENDOSCOPIC XENON ION LASER IN THE DIAGNOSIS OF GASTRIC CANCER |
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| 引用本文： | 萧树东,吴叔明,罗鸿仔,张德中,叶衍铭,杨远龙,李黎明. AUTOFLUORESCENCE EXCITED BY ENDOSCOPIC XENON ION LASER IN THE DIAGNOSIS OF GASTRIC CANCER[J]. 上海第二医科大学学报, 1990, 0(1) |
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| 作者姓名： | 萧树东 吴叔明 罗鸿仔 张德中 叶衍铭 杨远龙 李黎明 |
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| 作者单位： | Shanghai Institute of Digestive Disease，SSMU，Shanghai，Shanghai Institute of Digestive Disease，SSMU，Shanghai，Shanghai Institute of Digestive Disease，SSMU，Shanghai，Shanghai Institute of Digestive Disease，SSMU，Shanghai，Fudan University，Shanghai，Fudan University，Shanghai，Fudan University，Shanghai |
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| 摘 要： | Endoscopic xenon ion laser induced autofluorescence spectra in various gastric diseases were tested in 104 patients diagnosed by endoscopy and biopsy, including 28 gastric cancer, 9 gastric ulcer, 46 chronic atrophic gastritis, and 21 superficial gastritis. The autofluorescence spectrum excited with the 365 nm line of pulsed xenon ion laser was measured. The xenon ion laser beam having an output energy of 0.5 mJ with a duration of 0.6μs and a repetition rate of 10 Hz was used as the excitation source. A coaxial optical cable for laser light and autofluorescent light transmission was inserted via the biopsy channel of an endoscope into the cavity of stomach. The tip of opitcal cable was aimed at the gastric tissue and autofluorescence spectrum was plotted on X-Y recorder. As the monochromator scanned in the range 500-750 nm, a single-pulse fluorescence spectrum could be obtained by using an optical multichannel analyser, and then this fluorescence spectrum was stored in the computer. The whole procedure could be completed within 15 seconds. The results of the present study show that autofluorescence spectra of gastric cancer have characteristic peaks near 630 nm and 690 nm, while no such peaks appear in the spectra of the corresponding normal regions. A consistency of 75% was observed in gastric cancer as compared with the pathologic diagnosis. It is claimed that this is a harmless, safe, simple, and fast procedure in the diagnosis of gastric cancer.
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AUTOFLUORESCENCE EXCITED BY ENDOSCOPIC XENON ION LASER IN THE DIAGNOSIS OF GASTRIC CANCER |
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| Xiao Shudong Wu Shuming Luo Hongyu Zhang Dezhong. AUTOFLUORESCENCE EXCITED BY ENDOSCOPIC XENON ION LASER IN THE DIAGNOSIS OF GASTRIC CANCER[J]. Journal of Shanghai Second Medical University(Foreign Language Edition), 1990, 0(1) |
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| Authors: | Xiao Shudong Wu Shuming Luo Hongyu Zhang Dezhong |
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| Affiliation: | Xiao Shudong Wu Shuming Luo Hongyu Zhang Dezhong Shanghai Institute of Digestive Disease,SSMU,Shanghai Ye Yanming Yang Yuanlong Li Liming Fudan University,Shanghai |
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| Abstract: | |
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| Keywords: | autofluorescence endoscopy xenon ion laser gastric cancer characteristic peaks |
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