A case of recurrent bilateral pneumonia with fever. Diagnosis: microscopic polyangiitis |
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Authors: | Msaad S Yangui I Ben Amira S Kammoun K Boudawara T Ayoub A |
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Affiliation: | Service de Pneumo-Allergologie, CHU Hedi-Chaker, Sfax 3029, Tunisia. |
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Abstract: | Microscopic polyangiitis (MPA) is a rare systemic disease that usually presents as a pulmonary-renal syndrome. We describe 35-year-old men who presented with hemoptysis and bilateral alveolar opacities of the upper part of both lungs. The CT scan showed alveolar and round-glass opacities with a "mosaic-like" pattern. Bronchoalveolar lavage confirmed pulmonary hemorrhage. Renal biopsy was indicated because proteinuria revealed extracapillary glomerulonephritis. Laboratory tests showed a high level of serum antimyeloperoxidase-antineutrophil cytoplasmic antibody. We made a diagnosis of MPA. Cyclophosphamide and corticosteroid therapy was instituted and remission achieved. Through this case report, we discuss the diversity of the radio-clinical features of MPA. |
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Keywords: | Polyangéite microscopique Anticorps anti-cytoplasme des polynucléaires neutophiles Vascularites Pronostic |
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