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HB-VM模式与定量PCR关系
引用本文:陈洪涛,汲振余,赵翠林,孙爱民,金志宏.HB-VM模式与定量PCR关系[J].河南医学研究,2002,11(4):313-314.
作者姓名:陈洪涛  汲振余  赵翠林  孙爱民  金志宏
作者单位:河南省医学科学研究所肝病研究室,河南郑州,450052
摘    要:目的 :探讨血清HBVDNA水平与HBV标志物 (HBV M)表现模式的关系。方法 :对 12 0 7例慢性乙型肝炎患者进行血清HBVDNA荧光定量PCR分析 ,HBVM检测采用ELISA法。结果 :血清HBVDNA水平与HBVM表现模式有关 ,HBsAg与HBeAg的存在影响HBVDNA水平变化。结论 :HBeAg和HBVDNA有明显的相关 ,抗 HBe、抗HBc阳性者病毒未完全停止复制 ,只是复制水平降低

关 键 词:乙型肝炎病毒  乙肝病毒标志物  HBVDNA  荧光定量PCR
文章编号:1004-437X(2002)04-0313-02
修稿时间:2002年10月17

Relationship between the models of hepatitis B virus markers and Amplisensor-PCR
CHEN Hong tao,JI Zhen yu,ZHAO Chui lin,et al.Relationship between the models of hepatitis B virus markers and Amplisensor-PCR[J].Henan Medical Research,2002,11(4):313-314.
Authors:CHEN Hong tao  JI Zhen yu  ZHAO Chui lin  
Abstract:Objective: To explore the relation between the nuclear acid content of hepatitis B virus and hepatitis B virus markers.Methods: HBV DNA of 1 207 patients suffering from Chronic hepatitis B were quantified by Amplisensor ration PCR analysis Hepatitis B virus markers were detected by ELISA.Results: Serum HBV DNA content was related to hepatitis B virus markers.Conclusion: There is a significant correlation between HBeAg and HBV DNA,but the patients with positives Anti HBe and Anti HBc still have a few copies of HBV DNA.
Keywords:Hepatitis B Virus  HBV M  HBV DNA  Amplisensor  PCR
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