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Diagnostic management and outcomes of pulmonary tuberculosis suspects admitted to a central hospital in Malawi
Authors:L. G. Gawa  T. Reid  M. E. Edginton  M. Van Lettow  M. Joshua  A. D. Harries
Affiliation:1.Dignitas International, Zomba, Malawi;2.Zomba Central Hospital, Zomba Ministry of Health, Zomba, Malawi;3.Operations Research Unit, Médicins Sans Frontières, Operations Center Brussels, Luxembourg;4.International Union Against Tuberculosis and Lung Disease, Paris, France;5.University of Toronto, Dalla Lana School of Public Health, Toronto, Ontario, Canada;6.London School of Hygiene & Tropical Medicine, London, UK
Abstract:

Setting:

Zomba Central Hospital, Malawi.

Objective:

To determine diagnostic management and outcomes of pulmonary tuberculosis (PTB) suspects admitted to adult wards.

Design:

A retrospective, cross-sectional review of medical records of patients admitted to hospital between July and September 2010.

Results:

There were 141 PTB suspects. Sputum examination was requested and performed in 67 (48%) suspects, but none were smear-positive. Chest X-ray (CXR) was requested and performed in 26 (39%) suspects whose sputum smears were negative. Eleven suspects had a CXR suggestive of PTB: two were started on TB treatment and eight died before treatment started. Human immunodeficiency virus (HIV) status was known for 50 patients (35% of all suspects) on admission, all of whom were HIV-positive. HIV testing was requested for 37 patients, but was only performed in 12, five of whom were HIV-positive. Only one patient was referred for antiretroviral treatment. There were 41 (29%) deaths, eight of whom had probable TB and were not treated. In the remaining 33 patients who died, only nine (27%) had sputum smears examined and four (12%) had a CXR.

Conclusion:

The study shows inadequacies in the diagnostic management of PTB suspects in the Zomba Central Hospital, but suggests opportunities for improvement.
Keywords:PTB suspects   diagnosis   management   outcomes   Malawi
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