Sensitisation to aeroallergens among asthmatic and non-asthmatic adolescents living in a poor region in the Northeast of Brazil |
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| Authors: | E.C.S. Sarinho J. Mariano S.W. Sarinho D. Medeiros J.A. Rizzo S. Almerinda R D. Solé |
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| Affiliation: | 1. Departamento de Saúde Materno Infantil, Brazil;2. Medicina Clínica of Universidade Federal de Pernambuco, Brazil;3. Disciplina de Alergia, Imunologia Clínica e Reumatologia, Departamento de Pediatria, Universidade Federal de São Paulo, Brazil;1. The Ohio State University, Wexner Medical Center, Columbus, Ohio;2. Section of Infectious Diseases and Immunology, Department of Pediatrics, Nationwide Children''s Hospital, Columbus, Ohio;3. The Center for Biostatistics, The Ohio State University, Columbus, Ohio;1. Center for Environmental and Respiratory Health Research, Oulu, Finland;2. Respiratory Medicine Unit, Institute of Clinical Medicine, Oulu, Finland;3. Public Health, Institute of Health Sciences, University of Oulu, Oulu, Finland;4. Medical Research Center Oulu, Oulu, Finland;5. Respiratory Medicine Unit, Oulu University Hospital, Oulu, Finland;6. Faculty of Public Health, Thammasat University, Pathum Thani, Thailand;1. Arizona Respiratory Center, University of Arizona, Tucson, Ariz;2. Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Ariz;3. Centre for Research in Environmental Epidemiology (CREAL), CIBERESP, Universitat Pompeu Fabra, Barcelona, Spain |
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| Abstract: | ObjectivesTo assess the kind and frequency of sensitisation to aeroallergens (skin prick test - SPT) of asthmatic and non-asthmatic adolescents (13–14 years old) living in the city of Caruaru, Northeast of Brazil, and to analyse their exposure to some environmental factors.MethodA case-control study was conducted with asthmatic (50) and non-asthmatic (150) adolescents diagnosed by the International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire. All were submitted to SPT with aeroallergens (house dust mites, cat and dog epithelium, cockroaches, moulds and grass) and completed a questionnaire to evaluate their environmental exposure.ResultsThere were no significant differences between groups regarding gender, age, number of siblings and environmental exposure. Asthmatic subjects exhibited a higher frequency of positive SPTs than non-asthmatic subjects (54.0% vs 33.3%, p=0.009) mainly due to Periplaneta americana (34.0% vs 12.7%, p=0.0007 respectively) and Canis familiaris (20.0% vs 8.7%, p=0.029).ConclusionAlthough sensitisation to aeroallergens was high among non-asthmatic adolescents, asthma was associated with parental history of atopic disease and sensitisation to P. americana and Canis familiaris but not to D. pteronyssinus showing that local studies are mandatory for the tailoring of appropriate management of allergic diseases. |
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