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Discovery of MK-5046, a Potent,Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity |
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| Authors: | Iyassu K. Sebhat Christopher Franklin Michael M.-C. Lo David Chen James P. Jewell Randy Miller Jianmei Pang Oksana Palyha Yanqing Kan Theresa M. Kelly Xiao-Ming Guan Donald J. Marsh Jennifer A. Kosinski Joseph M. Metzger Kathryn Lyons Jasminka Dragovic Peter R. Guzzo Alan J. Henderson Marc L. Reitman Ravi P. Nargund Matthew J. Wyvratt Linus S. Lin | |
| Affiliation: | Departments of †Medicinal Chemistry;‡Drug Metabolism;§Metabolic Diseases (Obesity);∥Pharmacology;Merck Research Laboratories, Rahway, New Jersey 07065, United States;⊥AMRI, 26 Corporate Circle, Albany, New York 12212, United States | |
| Abstract: | ||
| Keywords: | MK-5046 bombesin receptor subtype-3 agonist obesity | |