| A Retrospective and Comparative Study of Familial and Non-familial Bullous Lichen Planus |
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| 作者姓名： | 黄长征 严小枫 杨凌云 张晶 田进 李家文 王椿森 涂亚庭 |
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| 作者单位： | Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Dermatology Union Hospital Tongji Medical College Huazhong University of Science and Technology，Wuhan 430022 China，Wuhan 430022 China，Wuhan 430022 China，Wuhan 430022 China，Wuhan 430022 China，Wuhan 430022 China，Wuhan 430022 China，Wuhan 430022 China |
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| 摘 要： | In order to compare the clinical characteristics of familial and non-familial bullous lichen planus (BLP), the archival data of 36 BLP patients with positive family history and 21 BLP patients with negative family history diagnosed according to the clinical features and histopathology were collected in our department from 1956 to 2003. The clinical features were analyzed and compared. There were significant differences between familial and non-familial BLP in age of onset, duration of disease and extension of eruption (P<0.01). It was concluded that familial BLP appeared to differ from the non-familial form in its earlier age of onset, longer duration of the disease, more extensive eruption and more tendency to involve nails. Hereditary factors may play a role in the pathogenesis of familial BLP.
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| 收稿时间： | 13 November 2006 |
A retrospective and comparative study of familial and non-familial bullous lichen planus |
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| Huang Changzheng,Yan Xiaofeng,Yang Lingyun,Zhang Jing,Tian Jin,Li Jiawen,Wang Chunsen,Tu Yating.A Retrospective and Comparative Study of Familial and Non-familial Bullous Lichen Planus[J].Journal of Zuazhong University of Science and Technology: Medical Edition,2007,27(3):336-338. |
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| Authors: | Huang Changzheng Yan Xiaofeng Yang Lingyun Zhang Jing Tian Jin Li Jiawen Wang Chunsen Tu Yating |
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| Institution: | Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430022, China |
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| Abstract: | In order to compare the clinical characteristics of familial and non-familial bullous lichen planus (BLP), the archival data of 36 BLP patients with positive family history and 21 BLP patients with negative family history diagnosed according to the clinical features and histopathology were collected in our department from 1956 to 2003. The clinical features were analyzed and compared. There were significant differences between familial and non-familial BLP in age of onset, duration of disease and extension of eruption (P<0.01). It was concluded that familial BLP appeared to differ from the non-familial form in its earlier age of onset, longer duration of the disease, more extensive eruption and more tendency to involve nails. Hereditary factors may play a role in the pathogenesis of familial BLP. |
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| Keywords: | familial non-familial bullous lichen planus |
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