108例HIV感染者/AIDS病人临床分析

目的了解艾滋病重点村艾滋病病毒(HIV)感染者和获得性免疫缺陷综合征(AIDS)临床表现的特点,及抗逆转录病毒治疗(ART)的效果. 方法对HIV感染者和AIDS病人的流行病学和临床资料加以归纳总结. 结果 AIDS病人72例.28例进行了丙肝抗体检测,仅1例阴性.69例AIDS病人进行了抗逆转录病毒治疗,服药后34例患者出现了不同程度的不良反应,16例退出治疗,50例AIDS病人坚持抗病毒治疗半年至1年半临床症状改善率94% 结论 ART确实大大减轻了患者的临床症状,但不良反应较大,影响了患者的服药依从性,部分病人出现耐药,药物的组合和选择均受到限制,探索适合贫困地区抗逆转录病毒治疗的新路已是当务之急.

Clinical analysis of 108 cases with HIV/AIDS

Aim To understand clinical characteristic of HIV/AIDS in one AIDS village in Fuyang,and determine the effect of the ART(antiretroviral therapy).Methods Analysis the epidemiological and clinical of 108 cases with HIV/AIDS.Results 69 AIDS cases were treated with ART.Side effects were found in 34 cases.16 cases stopped treatment on the half way.50 cases persisted in treatment.Clinical symptoms were well improved(94%),CD4 cell counts were risen(66%),and HIV viral loads were descended 10 times and undetectable(62%).16 cases had resistance.Conclusion It is very important to protect the high risk groups and intervene in high risk behavior.ART(antiretroviral therapy) is the most effective method in curing HIV/AIDS,and its clinical effectiveness is closely related to the clinical compliance.