超声斑点追踪及成像技术评价主动脉瓣反流患者左室扭转运动

内容:目的:本研究旨在应用二维斑点追踪及成像技术评价主动脉瓣反流(AR)患者左室二维应变及扭转运动,以期探讨其左室功能改变.方法:95例经二维超声心动图诊断为单纯性AR患者,按照反流程度分为轻、中、重度组.30例健康志愿者.行常规二维超声心动图并二维斑点追踪成像检查,采集左室心尖四腔及短轴各节段动态图像,应用EchoPAC工作站软件行脱机分析.比较不同程度AR患者和健康志愿者左室功能改变.结果:①各组间年龄、性别、身高、体重、体表面积和心率的差异均无统计学意义(P>0.05).②轻度AR组与正常对照组比较舒张末期左室内径、收缩末期左室内径、舒张末期左室容积、收缩末期左室容积、左室射血分数、二尖瓣口舒张期E峰、A峰及E/A比值差异均无统计学意义(P>0.05).中度AR组及重度AR组与正常对照组相比,舒张末期左室内径、舒张末期左室容积增大(P<0.05).中度AR组与对照组相比左室射血分数、二尖瓣口舒张期E、A峰及E/A比值的差异均无明显统计学意义(P>0.05).重度AR组左室射血分数与对照组相比有显著差异(P<0.05),但二尖瓣口舒张期E、A峰及E/A比值的差异则无明显统计学意义(P>0.05).③轻度AR组心底、心尖部旋转及扭转曲线与正常对照组差异无明显统计学意义(P>0.05).中度AR组心底、心尖部旋转及扭转角度较正常对照组明显增大(P<0.05).而重度AR组心底、心尖部旋转及扭转角度则较正常对照组明显减小(P<0.05).

Assessment of Left Ventricular Function in Patients with Aortic Regurgitation by Two Dimensional Strain Imaging

In this study, we examined patients with simple aortic regurgitation （in accordance with the degree of regurgitation, patients were divided into mild. moderate and severe group）which diagnosis by two-dimensional echocardiography, using conventional two- dimensional color Doppler echocardiography. We received two-dimensional gray scale images of parastemal left ventricular short axis view of mitral valve and left ventricular short axis view of apex, all the images were stored in a disc. Echo PAC workstation with STI imaging analysis software was used. Two-dimensional strain, the movement of change in rotation and twist in left ventricular were compared between aortic regurgitation group and normal control group.