经尿道电切术治疗表浅性膀胱癌合并良性前列腺增生的临床分析

目的探讨合并良性前列腺增生（BPH）的表浅性膀胱癌（SBC）患者同期行经尿道膀胱肿瘤及前列腺电切术的有效性及安全性。方法回顾性研究32例（研究组）同期行经尿道膀胱肿瘤电切（TURBT）及经尿道前列腺电切（TURP）患者和35例（对照组）仅行TURBT的患者，术后均按疗程行羟基喜树碱20mg膀胱灌注，两组在年龄、肿瘤大小、肿瘤分期分级等方面差异均无统计学意义（P〉0．05）。结果所有患者均顺利完成手术，随访期限为1—3年，平均1．8年。研究组膀胱肿瘤复发率为46．9％，对照组复发率为45．7％，平均复发时间研究组为16个月、对照组为13个月，两组间差异均无统计学意义（P〉0．05）。研究组术后复发病例中未发生前列腺窝种植。结论对于合并BPH的SBC患者，同期行TURBT＋TURP术是比较安全有效的方法，同时不增加前列腺窝内肿瘤种植的几率。

Clinical investigation of simultaneous transurethral resection for treatment of superficial bladder tumor complicated with benign prostatic hyperplasia

Objective To evaluate the safety and clinical effect of simultaneous transurethral resection of superficial bladder tumor （TURBT） and transurethral resection of prostate （TURP）. Methods The clinical data of 67 patients with SBC and BPH were retrospectively studied. The patients in test group（ n = 32） underwent TURBT and TURP at the same time while those in control group received TURBT only. All the patients accepted the irrigation of bladder by Hydroxycamptothecin （20 milligram one time） according to the course of treatment. There was no significant difference between two groups in age, tumor size, tumor stage and grade （ P 〉 0.05 ）. Results All patients were successfully operated. The following - up period ranged from one to three years, the average time was one point eight years. The bladder cancer recurrence rate was 46.9% and 45.7% in the control group. The average recurrent time was 16 months in the test group and 13 months in the control group. There were no significant differences between the two groups neither in average recurrence rates nor recurrent time （P 〉 0.05 ）. There were no prostatic urethra implantation recurrence occurred in test group. Conclusion Simultaneous TURBT and TURP is a safe and effective alternative treatment for the patients of superficial bladder cancer complicated with benign prostatic hyperplasia, and it would not increase tumor implantation at the prostatic urethra.