伴微血管侵犯原发性肝癌根治术患者短期预后的影响因素分析

目的 探讨影响伴微血管侵犯(MVI)原发性肝癌根治术患者短期预后的危险因素,为临床改善短期预后提供合理参考依据.方法 回顾性分析2017年12月至2018年12月期间在南阳市第一人民医院进行根治术治疗的98例伴MVI原发性肝癌患者的临床资料,术后1年随访资料完整,将术后1年内肝癌复发的患者纳入复发组,将1年内癌症未复发...

Influencing factors of short-term prognosis in patients undergoing radical hepatectomy with microvascular invasion

【Objective】To explore the risk factors affecting the short-term prognosis of patients with primary hepatocellular carcinoma with microvascular invasion(MVI)radical surgery,in order to provide a reasonable reference for clinical improvement of short-term prognosis.【Methods】The clinical data of 98 patients with primary liver cancer with MVI who underwent radical surgery in our hospital from December 2017 to December 2018 were retrospectively analyzed.The data of 1-year follow-up after surgery was complete,and patients with liver cancer who relapsed within 1 year after surgery were included in the relapse group,and patients with cancer who did not relapse within 1 year were included in the non-relapse group.The general information of the two groups was compared,and the factors that might affect the short-term prognosis of patients with radical hepatectomy with MVI were included in the independent variables and values were assigned to them.Multiple logistic regression analysis was used to find out the risk factors affecting the short-term prognosis of patients with primary hepatoma with MVI.【Results】The preliminary single factor analysis and multiple logistic regression analysis results showed that tumor margin≥1 cm,tumor margins not smooth,multiple tumors,incomplete capsule,and abnormal AFP might all be the risk factors that affected the short-term prognosis of patients with primary hepatoma with MVI(OR>1,P<0.05).【Conclusion】Tumor resection margin≥1 cm,tumor margins not smooth,multiple tumors,incomplete capsule,abnormal AFP are all risk factors that affect the short-term prognosis of patients with primary hepatocellular carcinoma with MVI.It is recommended that during the course of radical surgery,the patient should be evaluated whether the patient is accompanied by the above-mentioned risk factors,and timely targeted response measures should be formulated to better improve the patient's prognosis.