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THE INFLAMMATORY RESPONSE IN THE SYNOVIUM OF A PATIENT WITH ROSS RIVER ARBOVIRUS INFECTION |
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| Authors: | R. A. HAZELTON C. HUGHES J. G. AASKOV |
| Affiliation: | Senior Lecturer in Medicine (Rheumatology), University of Queensland Department of Medicine, Princess Alexandra Hospital, Brisbane;Medical Registrar, Queen Elizabeth It Jubilee Hospital, Nathan, Brisbane;Senior Immunologist, Queensland Institute of Medical Research, Herston, Brisbane |
| Abstract: | Ross River virus has been incriminated in the etiology of many sporadic and epidemic cases of polyarthritis in Australia and the Pacific. Both synovium and synovial exudate fluid recovered from the knee of an epidemic polyarthritis patient showed a predominantly mononuclear leucocyte infiltrate. Infectious virus could not be recovered from the synovial exudate. Functional natural killer cells were detected in the synovial fluid. Their level of cytotoxic activity was similar to that detected in the peripheral circulation. (Aust NZ J Med 1985; 15: 336–339.) |
| Keywords: | Viral polyarthritis synovial histology natural killer cells |