| 煤工尘肺及合并肺癌肺组织Bcl-2基因表达及意义 |
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| 引用本文： | 范雪云,马庆坤,张岩松,马骏,张翔. 煤工尘肺及合并肺癌肺组织Bcl-2基因表达及意义[J]. 工业卫生与职业病, 2011, 0(5): 286-289 |
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| 作者姓名： | 范雪云 马庆坤 张岩松 马骏 张翔 |
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| 作者单位： | 河北联合大学公共卫生学院;唐山钢铁集团职业病防治所;国家安全生产监督生产管理局职业医学研究所; |
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| 摘 要： | 目的 检测煤工尘肺及合并肺癌肺组织Bcl-2基因蛋白表达情况,探讨煤工尘肺与肺癌的关系及其分子学机制.方法 收集煤工尘肺及煤工尘肺合并肺癌患者尸解病例为研究对象.依据病理诊断,选择煤工尘肺54例,尘肺合并肺癌10例.选取30例煤工尘肺病变旁正常肺组织(组织结构正常、肺泡间隔无破坏、肺泡腔内未见渗出)作为对照肺组织.利用...
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| 关 键 词： | 煤工尘肺 煤工尘肺合并肺癌 Bcl-2基因蛋白 免疫组织化学法 |
Expression and Its Significance of Bcl-2 Protein in Lung Tissues of Coal Worker's Pneumoconiosis Complicated with Lung Cancer |
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| FAN Xue-yun,MA Qing-kun,ZHANG Yan-song,MA Jun,ZHANG Xiang. Expression and Its Significance of Bcl-2 Protein in Lung Tissues of Coal Worker's Pneumoconiosis Complicated with Lung Cancer[J]. Industrial Health and Occupational Diseases, 2011, 0(5): 286-289 |
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| Authors: | FAN Xue-yun MA Qing-kun ZHANG Yan-song MA Jun ZHANG Xiang |
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| Affiliation: | FAN Xue-yun,MA Qing-kun,ZHANG Yan-song,MA Jun,ZHANG Xiang( School of Public Health,Hebei United University,Tangshan 063000 China) |
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| Abstract: | Objective To detect the expression of Bcl-2 protein in lung tissues of coal worker's pneumoconiosis(CWP)complicated with lung cancer and to explore the relationship between CWP and lung cancer and its molecular mechanism.Methods The dissected lung specimens of CWP were collected.Based on pathologic diagnosis,54 cases of CWP and 10 cases of CWP complicated with lung cancer were selected as the study subject.Since to obtain healthy persons' lung tissue was very difficult,the lung tissues of normal structure a... |
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| Keywords: | CWP CWP complicated with lung cancer Bcl-2 protein Immunohistochemistry |
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