银杏叶胶囊合并综合康复训练治疗慢性精神分裂症临床观察

目的：探讨银杏叶胶囊合并综合康复训练治疗慢性精神分裂症患者临床疗效。方法：对110例经系统抗精神病药物治疗12周以上,且疗效欠佳的长期住院慢性精神分裂症患者,加用银杏叶胶囊合并综合康复训练进行为期12周的动态治疗观察;治疗前后,用阳性与阴性症状量表（PANSS）和抗精神病药物治疗中需处理的不良反应症状量表（TESS）评定临床疗效和不良反应。结果：银杏叶胶囊合并综合康复训练治疗长期住院慢性精神分裂症患者疗效显著,临床总有效率为96.36%,愈显率（治愈＋显效）为67.27%,显著优于单用抗精神病药物合并综合康复训练治疗;银杏叶胶囊无特殊副反应,且具有减轻抗精神病药物副反应的作用。结论：银杏叶胶囊能提高抗精神病药物治疗慢性精神分裂症的疗效,减轻抗精神病药物副反应,是治疗长期住院慢性精神分裂症患者的安全、有效药物。

Clinical evaluation of ginkgo leaf capsule combined with comprehensive rehabilitation training in treating chronic schizophrenia

AIM：To evaluate the therapeutic effects of treating chronic schizophrenia with ginkgo leaf capsule combined with comprehensive rehabilitation training. METHODS：110 chronic schizophrenia patients who had been treated with systemic antipsychotic for more than 12 weeks with unsatisfactory therapeutic effects and a long history of hospitalization were enrolled in this study. Ginkgo leaf capsule combined with comprehensive rehabilitation training was applied for 12 weeks and the therapeutic effects were evaluated. The positive and negative syndrome scale （PANSS） and treatment emergent symptom scale（TESS） for the side effects that needed to be treated during treating were used to evaluate the therapeutic effects and side effects. RESULTS：The treatment of ginkgo leaf capsule combined with comprehensive rehabilitation training was effective for the chronic schizophrenia patients with a long history of hospitalization,the total clinical effective rate was 96.36% and the cure rate together with the apparent rate was 67.27%,which were significantly better. CONCLUSION：Ginkgo leaf capsule improves the therapeutic effects of antipsychotic in the treatment of chronic schizophrenia and reduces the side effects,so it is a safe and effective drug for treating the chronic schizophrenia patients with a long history of hospitalization.