多途径给药治疗输卵管阻塞陛不孕症的临床观察

目的：观察中药多途径给药治疗输卵管阻塞性不孕症的疗效与安全性。方法：将77例患者随机分为综合治疗组（中药口服联合中药灌肠、热敷及静点丹参注射液）42例和口服药物组（单纯中药口服）35例．观察两组治疗前后的输卯管通畅程度、妊娠情况、血流变指标、安全性指标和不良反应。结果：两组有效率分别为81．0％、54．3％（P〈0．05）；妊娠率分别为42．9％、22．9％（P〈0．05）；治疗前后月经情况和血流变指标两组无统计学差异；病程、年龄与疗效及妊娠率无统计学差异；多途径给药组副反应相对较多，但程度较轻，不影响继续治疗。结论：多途径综合治疗组比单纯口服中药组的疗效更好。

Clinical study on traditional Chinese medicine treating female sterility of fallopian tubal blockage with multiplex herbal administration

Objective：To observe clinical effects and side reactions of traditional Chinese medicine treating fallopian tubal blockage with multiplex herbal administration.Methods：All 77 patients with sterility of tubal blockage were randomly divided into multiplex treated group （in which Chinese herbs were administrated by mouth combined with rectum,abdomen skin and intravenous dipping,n=42） and the control group,Chinese herbs were taken orally（n=35）.Results：The improving rate of the tubal patent evaluated by hysterosalpingogram of the treated group and the control one was 81.0% and 54.3% respectively （P〈0.05）.The pregnant rate of these two groups were 42.9% and 22.9% respectively,with significant difference.There was no significant difference between persistent time of desease or ages and pregnant rates.Conclusion：Compared with the control group,the multiplex treated group can bring better clinical effects on tubal patent extent and pregnancy rate significantly.