Association of HLA and renal cell carcinoma |
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| Authors: | W C DeWolf P H Lange R Shepherd S Martin-Alosco E J Yunis |
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| Affiliation: | 1. Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA;2. Department of Surgery, Beth Israel Hospital, Boston, Massachusetts, USA;3. Department of Urologic Surgery, University of Minnesota, Minneapolis, Minnesota, USA;4. Northeast Regional Red Cross Blood Program, Boston, Massachusetts, USA |
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| Abstract: | HLA-A,B,C, and DR antigen frequencies were studied in a patient population with a history of renal cell carcinoma. HLA-DR5 was found in 54% of patients, which is significantly elevated over control values (20%; p less than .01). On the other hand, HLA-A,B, and C locus antigen frequencies were not abnormal compared to controls. |
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| Keywords: | Address requests for reprints to William C. DeWolf M.D. Division of Immunogenetics Sidney Farber Cancer Institute 44 Binney Street Boston MA 02215. |
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