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静止性脑小血管病与认知功能障碍的关系
引用本文:李俊雯,黄敬.静止性脑小血管病与认知功能障碍的关系[J].上海医药,2014(17):9-12.
作者姓名:李俊雯  黄敬
作者单位:同济大学医学院附属第十人民医院神经内科,上海200072
摘    要:脑小血管病(cerebral small vessel disease, CSVD)在影像学上主要以腔隙性梗死、白质病变和脑微出血的形态存在。静止性CSVD与认知功能障碍密切相关,其导致的认知功能障碍主要表现为执行功能障碍、反应迟钝和注意力下降等,与病灶部位、数量和大小相关。本文就静止性CSVD的主要影像学表现及其与认知功能障碍的关系作一综述,以期加深临床医生对静止性CSVD及其危害的认识并提高识别率,由此尽早干预而延缓患者认知功能障碍的发生和发展,提高患者的生活质量。

关 键 词:静止性脑小血管病  认知功能障碍  腔隙性梗死  白质病变  脑微出血

Relationship between silent cerebral small vessel disease and cognitive impairment
LI Junwen,HUANG Jing.Relationship between silent cerebral small vessel disease and cognitive impairment[J].Shanghai Medical & Pharmaceutical Journal,2014(17):9-12.
Authors:LI Junwen  HUANG Jing
Institution:(Department of Neurology, the lOth People's Hospital affiliated to School of Medicine, Tongji University, Shanghai 200072, China)
Abstract:The imaging features of cerebral small vessel disease (CSVD) include 1acunar infarcts, white matter lesions, cerebral microbleeds. Silent CSVD is closely associated with cognitive impairment. The decline in executive function, processing speed and memory problem are the main performance of the cognitive dysfunction caused by silent CSVD, which is associated with focal areas, quantity and size. Here we summarize the imaging features of silent CSVD and the relationship between silent CSVD and cognitive impairment for the purpose of early recognition and management of silent CSVD so as to delay the onset and development of cognitive impairment and improve the patients’ quality of life.
Keywords:silent cerebral small vessel disease  cognitive impairment  lacunar infarcts  white matter lesions  cerebral microbleeds
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