| 先天性巨结肠非手术治疗研究进展 |
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| 引用本文： | 王吉,李智. 先天性巨结肠非手术治疗研究进展[J]. 临床小儿外科杂志, 2022, 21(2): 186-190 |
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| 作者姓名： | 王吉 李智 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院小儿外科,武汉 430030 |
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| 基金项目： | 国家自然科学基金项目(81400579)。 |
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| 摘 要： | 先天性巨结肠(Hirschsprung's disease,HSCR)是一种常见的先天性消化道发育畸形,以病变肠管神经节细胞缺乏为特征,发病率约1/5000,男女比例约4:1.HSCR的治疗主要包括手术治疗和非手术治疗,目前通过手术切除无神经节细胞肠段及移行段仍为HSCR的主要治疗方式.近年来,国内外学者对HSCR非手...
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| 关 键 词： | Hirschsprung病/治疗 Hirschsprung病/外科学 扩肛 灌肠 方剂 肉毒素 生物反馈 干细胞治疗 |
Recent advances of non-surgical treatment of Hirschsprung's disease |
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| Wang Ji,Li Zhi. Recent advances of non-surgical treatment of Hirschsprung's disease[J]. Journal of Clinical Pediatric Surgery, 2022, 21(2): 186-190 |
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| Authors: | Wang Ji Li Zhi |
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| Affiliation: | (Department of Pediatric Surgery,Affiliated Tongji Hospital,Tongji Medical College,Huazhong University of Science&Technology,Wuhan 430030,China) |
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| Abstract: | As a congenital bowel disorder,Hirschsprung's disease(HSCR)is characterized by the absence of intestinal ganglion cells with a prevalence of 1/5000 and a male-to-female ratio of 4:1.Its treatment options include surgery and non-surgical measures.The major treatment remains surgical resection by removing ganglion-free intestine and transitional segments.Domestic and foreign scholars actively exploring non-surgical option have concluded that it plays an important role in resolving defecation problems before and after operation.This review summarized non-surgical option of HSCR from the aspects of anal dilation and enema,traditional Chinese medicine,botulinum toxin injection,biofeedback and stem-cell therapies. |
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| Keywords: | Hirschsprung Disease/TH Hirschsprung Disease/SU Anal Dilatation Enema Chinese Medical Formula Botulinum Toxin Biofeedback Therapy Stem-cell Therapy |
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