甲亢合并2型糖尿病患者血清学相关指标检验及临床意义分析

目的 探讨甲状腺功能亢进症(甲亢)合并2型糖尿病患者血清学相关指标检验及临床意义.方法 60例甲亢患者,依据是否合并2型糖尿病分为对照组(未合并)与合并组(合并),各30例.两组均于清晨空腹抽取静脉血,检测甲状腺功能[三碘甲状腺原氨酸(T3)、甲状腺素(T4)、游离T4(FT4)及游离T3(FT3)、促甲状腺激素(TS...

Clinical significance of serological indexes in patients with hyperthyroidism and type 2 diabetes mellitus

Objective To discuss the clinical significance of serological indexes in patients with hyperthyroidism and type 2 diabetes mellitus.Methods A total of 60 patients with type 2 diabetes mellitus were divided into control group (uncomplicated) and combined group (combined) according to whether they had type 2diabetes mellitus or not,with 30 cases in each group.In both groups,venous blood was drawn in the early morning on an empty stomach,and thyroid function[triiodothyronine (T₃),thyroxine (T₄),free T₄ (FT₄) and free T₃ (FT₃),thyroid stimulating hormone (TSH)]and blood glucose indexes[C-peptide (CP),glucose (GLU),insulin (INS)and glycosylated hemoglobin (HbA1c)]were measured.Results The T₃ (7.68±0.75) nmol/L,T₄ (252.96±25.36) nmol/L,FT₃ (15.26±2.42) pmol/L,FT₄ (44.09±4.87) pmol/L in the combined group were significantly higher than (7.21±0.89) nmol/L,(236.36±27.64) nmol/L,(13.60±2.05) pmol/L,(40.38±4.81) pmol/L in the control group,and the TSH (0.007±0.001) mIU/L was significantly lower than (0.110±0.020) mIU/L in the control group,and the difference was statistically significant (P<0.05).The CP (3.46±0.75) ng/ml,GLU (13.23±4.82) mmol/L,INS (10.12±2.15)μU/ml,HbA1c (14.03±3.15)%of the combined group were significantly higher than (2.79±0.75) ng/ml,(5.23±0.84) mmol/L,(5.65±1.02)μU/ml,(5.14±0.61)%of the control group,and the difference was statistically significant (P<0.05).Conclusion Patients with hyperthyroidism with type 2 diabetes mellitus will have certain abnormalities in serological index tests,clinical attention should be paid to avoid misdiagnosis and missed diagnosis.