Effect of cigarette smoking on prepulse inhibition of the acoustic startle reflex in healthy male smokers |
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| Authors: | V Kumari Stuart A Checkley Jeffrey A Gray |
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| Institution: | (1) Institute of Psychiatry, University of London, De Crespigny Park, London SE5 8AF, UK, GB |
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| Abstract: | The present study investigated the effects of cigarette smoking on prepulse inhibition (PPI) of the acoustic startle reflex
in healthy men. Cigarette smoking in a group of overnight smoking-deprived smokers increased PPI as compared to the smoking-deprived
condition. This finding is consistent with previous animal studies showing that nicotine increases PPI of the acoustic startle
reflex. In addition, cigarette smoking also reduced startle amplitude during the first 6–7 min of the post-smoking session.
Received: 4 March 1996 / Final version: 17 June 1996 |
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| Keywords: | Prepulse inhibition Acoustic startle reflex Cigarette smoking Nicotine |
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