Clinical-radiologic heterogeneity of occipital neuralgiform pain as multiple sclerosis relapse |
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Authors: | De Santi Lorenzo Monti Lucia Menci Elisabetta Bellini Matteo Annunziata Pasquale |
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Institution: | From the Neurological and Behavioral Sciences, University of Siena (P. Annunziata and L. De Santi);Neuroradiology Unit, S. Maria alle Scotte Hospital, Siena, Italy (L. Monti, E. Menci, and M. Bellini). |
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Abstract: | Occipital neuralgia may be related to traumatic, compressive, or inflammatory injury to the occipital nerve or C2 radicular level and cervical spinal cord lesions. We report a series of 3 patients with definite relapsing-remitting multiple sclerosis (MS) who experienced sudden occipital neuralgiform pain with or without diminished sensation in the cervical region and associated with magnetic resonance imaging (MRI) evidence of a new active or new T2-weighted demyelinating C2 cervical lesion. We suggest that sudden paroxysmal occipital pain may signal relapse of MS and cervical MRI with gadolinium should be considered; these patients show good clinical response to high-dose intravenous corticosteroids. |
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Keywords: | occipital neuralgia multiple sclerosis pain relapse |
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