| 慢性牙周炎病变部位白细胞介素-8表达的初步研究 |
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| 引用本文： | 孙江,邹韵秋,马芸.慢性牙周炎病变部位白细胞介素-8表达的初步研究[J].广东牙病防治,2005,13(1):16-18. |
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| 作者姓名： | 孙江 邹韵秋 马芸 |
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| 作者单位： | 1. 大连市口腔医院,辽宁,大连,116021
2. 深圳市人民医院口腔医学中心 |
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| 基金项目： | 深圳市卫生科技计划项目基金资助 (2 0 0 0 0 4 0 68) |
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| 摘 要： | 目的探讨牙龈组织中自细胞介素-8(IL-8)与慢性牙周炎的关系。方法采用免疫组化法检测32例牙龈组织样本(16例健康者，16例慢性牙周炎患者)，分析IL-8的检出率及IL-8分泌细胞在牙龈组织中的分布。结果慢性牙周炎患者中的IL-8的检出率均高于健康者，IL-8阳性细胞分布于牙龈的上皮和结缔组织中。结论研究结果提示IL-8参与了牙周炎的病理过程。
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| 关 键 词： | IL-8 慢性牙周炎 牙龈组织 白细胞介素—8 病变部位 患者 检出率 提示 目的 样本 |
Preliminary Study on IL-8 Expression in Inflammatory Sites of Chronic Periodontitis Patients |
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| SUN Jiang,ZOU Yunqiu,MA Yun.Preliminary Study on IL-8 Expression in Inflammatory Sites of Chronic Periodontitis Patients[J].Journal of Dental Prevention and Treatment,2005,13(1):16-18. |
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| Authors: | SUN Jiang ZOU Yunqiu MA Yun |
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| Institution: | SUN Jiang *,ZOU Yunqiu,MA Yun. * Dalian Stomatological Hospital,Dalian 116021 |
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| Abstract: | Objective To explore the relationship between interleukin-8 (IL-8) and chronic periodontitis (CP). Methods Immuno-histo-chemistry technique was used to measure the levels of IL-8 and to identify the IL-8 positive cells in gingival tissue in 32 samples (16 healthy volunteers, 16 CP patients). Results The levels of IL-8 in CP group were significantly higher than that in healthy group and the IL-8 positive cells located in gingival epithelium and gingival connective tissue. Conclusion IL-8 took part in the pathological process of periodontitis. |
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| Keywords: | Chronic periodontitis IL-8 Gingival tissue |
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