| 盐酸布比卡因冻干乳剂的制备 |
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| 引用本文： | 王鸿,杨纲,梁文权. 盐酸布比卡因冻干乳剂的制备[J]. 海峡药学, 2004, 16(4): 21-22 |
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| 作者姓名： | 王鸿 杨纲 梁文权 |
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| 作者单位： | 浙江医学高等专科学校,杭州,310053;浙江大学药学院2001届本科毕业生;浙江大学药学院,杭州,310031 |
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| 摘 要： | 目的研究乳剂所用的支撑剂的种类、用量对冷冻干燥制备冻干乳剂的影响。方法采用冷冻干燥法制备盐酸布比卡因冻干乳荆，并根据干乳剂的物理特性和外观考察支撑剂的用量。结果采用一定比例的混合支撑剂的冻干乳剂的质量和外观优于使用单一支撑剂的冻干乳剂。结论支撑剂的用量和种类对干冻干乳剂的质量有非常重要的作用。
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| 关 键 词： | 盐酸布比卡因 冻干乳剂 |
| 文章编号： | 1006-3765(2004)04-0021-02 |
Preparation of the Dry Emulsion of Bupivicaine Hydrochloride |
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| WANG Hong ,YANG Cang ,LIANG Weng-quan. Preparation of the Dry Emulsion of Bupivicaine Hydrochloride[J]. Strait Pharmaceutical Journal, 2004, 16(4): 21-22 |
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| Authors: | WANG Hong YANG Cang LIANG Weng-quan |
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| Affiliation: | WANG Hong 1,YANG Cang *,LIANG Weng-quan 2 |
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| Abstract: | OBJECTIVE Study the effect of the suport agent's kind and dosage to the preparation of the dry emulsion.METHODS Use the lyophilization method to prepare the dry emulsion of bupivicaine hydrochloride,and select the kind and dosage of the support agent by the physical property and the appearance of the dry emulsion.RESULTS The quality and appearance of the dry emulsion,which is used mixed support agents,arebetter than that which is used single support agent.CONCLUSION The kind and dosage of the support agent have the important effect to the quality of the dry emulsion. |
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| Keywords: | Bupivicaine hydrochloride Lyophilization dry emulsion |
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