广西壮族自治区2002年实验室确诊麻疹病例监测结果分析

目的　了解麻疹实验室的监测状况和分析其监测结果。方法　对 2 0 0 2年从广西壮族自治区各地收集到的799例疑似麻疹病例的血清标本检测麻疹IgM抗体 ,并结合其个案调查资料进行分析。结果　发现实验室确诊麻疹病例有以下特征 :6 3.76 %的病例发生在 4～ 6月 ,78 83 %的病例 <1 5岁 ,81.5 9%的病例无麻疹疫苗 (MV)免疫史或免疫史不详 ,2.3 9%的病例未表现出咳嗽、卡他性鼻炎、结膜充血这三种症状的其中之一 ,出疹 4～ 7d后采血的麻疹IgM抗体阳性率高于≤ 3d。 结论　应根据现实条件将MV复种年龄从 7岁提前到 4岁 ,对预测的麻疹高危县进行MV强化免疫 ,有效降低麻疹发病率。同时 ,加强麻疹实验室网络建设 ,提高麻疹实验室监测质量

Analysis on Surveillance of Laboratory Diagnosed Measles Case in Guangxi in China in 2002

Objective In order to get information about the surveillance condition and analyses surveillance effects of laboratory for measles. Methods the serum samples of 799 cases of suspected measles have been collected from Guangxi,they were tested for specific measles IgM Ab in laboratory with the analysis of single case investigation materials. Results We found that the laboratory diagnosed cases showed several features below:63.76% cases appeared in April to June,78.83% cases were children younger than 15 years old,81.59% cases did not have measles vaccination experience or the vaccination history was unclear, 2.39% diagnosed cases did not have one of the clinic phenomenon such as cough,catarrhal rhinitis,and conjunctiva bleeding.The measles IgM Ab positive rate was higher in cases who behave eruption on day 4-7 than on day 0-3. Conclusion The results showed that the second vaccination time should be advanced from the children in 7 years old to 4 years old according to current condition in Guangxi. Moreover,immunization should be practiced in different batch and areas in counties with high-risk of measles to reduce the incidence of measles.The construction of measles surveillance network should also be enhanced in order to increase the surveillance quality.