氟比洛芬酯在妇科术后镇痛中的应用

目的本研究拟将氟比洛芬酯应用于术后病人自控静脉镇痛,以观察其镇痛效果。方法将60例全身麻醉下接受妇科开腹手术的女性患者随机分为两组,在术后开始应用不同配方的镇痛泵,分别为舒芬太尼组（S组）和舒芬太尼＋氟比洛芬酯组（SF组）。于术后1h、4h、8h、24h和48h随访患者,记录两组镇痛效果,累计镇痛药消耗量及不良反应。结果两组病人的人口统计学无显著差异。术后各个时间点的静息和活动VAS评分均没有显著差异。SF组的舒芬太尼消耗量从术后4h开始明显少于S组。恶心呕吐发生率没有统计学差异。结论镇痛泵中加入氟比洛芬酯可以使术后舒芬太尼的用量减少,而疼痛评分和副作用发生率没有变化。

Application of Flurbiprofen on Postoperative Analgesia in Gynecological

Objective This study is designed to observe the analgesic effect of flurbiprofen in postoperative patient-controlled intravenous analgesia.Methods 60 female patients scheduled for gynecologic abdominal surgery under general anesthesia were randomly assigned to either sufentanil group（S group） or sufentanil＋flurbiprofen group（SF group） as postoperative patient-controlled intravenous analgesia.At 1h,4h,8h,24h and48h postoperatively,patients were followed and analgesic effect,total analgesic consumption and adverse reactions were recorded.Results There were no significant differences regarding the demographic data.VAS scores at rest and activity were not significantly different.Sufentanil consumption of SF group from 4 hours was significantly less than S group.The incidence of nausea and vomiting was not statistically significant.Conclusion Analgesia added flurbiprofen can reduce the amount of postoperative sufentanil,and pain scores and incidence of side effects did not change.